MST-Department of Medical Surgical Nursing and Pre-clinical Services

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    Determinants of Timely Referral and Safe Transport of Neonates Referred to and those Transferred Out of Makueni County Referral Hospital, Kenya
    (Kenyatta University, 2024-12) Iluka, Francisca Nduku
    Internationally, 2.5 million babies lose their lives before first 28 days of life, many of the deaths occurs in the under developed countries and a third occurs on day one of life. According to the World Health Organization, many neonate deaths are preventable by simple interventions. The primary goal of the study was to establish determinants of timely referral and safe transport of neonates in Makueni County Referral Hospital. The study employed cross-sectional study design. The researcher collected data from 50 neonates through consecutive sampling. The researcher used a self-administered questionnaire, document reviews of the patients’ files and structured data checklist. Patients condition on admission was obtained from the health record. The researcher analyzed the data quantitatively using the Statistical Package for Social Sciences version 26 (SPSS V26). The data obtained was summarized using frequency tables. Inferential statistics such as Chi-square tests Fishers Exact, bivariate and multivariate analysis were used to test for associations. Graphs, text, tables and pie charts were used to present the ultimate results. In total 50 admitted neonates were recruited to the study and results analyzed. According to the study findings, the researcher found out that there was no significant association between timely referral and safe transport and neonatal and maternal variables. Conversely, analysis of institutional characteristics highlights several significant factors associated with the likelihood of timely referral and safe transport during a referral. Patients who did not receive stabilization were found to be more prone to experiencing a lack of timeliness and safe transport during referral (P=0.004), patients who did not undergo vital signs monitoring were 9.25 times more prone to experiencing delays and unsafe transportation (P = 0.035). The results suggest that patients with a response time exceeding 2 hours were more likely to face a lack of timeliness and safe transport during referral (P=0.032). The availability of an ambulance emerged as a significant factor, with 59.5% (25) reporting waiting for an ambulance as the reason for the delay. The study concludes that institutional factors influenced safe transport and timely referral to include patient stabilization, vital signs monitoring, response time for referral, and the availability of an ambulance. The study recommends that ambulances should be availed timely, in adequate numbers, and be equipped with the necessary drugs and equipments so that in the event of a problem, the healthcare provider can intervene appropriately. Also, hospitals should be supplied with all the necessary equipments and drugs to aid in stabilization of patients.
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    Patient Safety Culture among Health Care Professionals at the Kakamega County Referral Hospital, Kenya
    (Kenyatta University, 2025-05) Mulusa, Elizabeth Osaga
    Patient safety is a crucial global measure of healthcare quality, as emphasized by the World Health Organization (WHO). A poor safety culture among healthcare professionals can lead to more adverse events, longer hospital stays, increased healthcare costs, and higher morbidity and mortality rates. A significant challenge in this area is the complex assessment of patient safety, with existing literature focusing mostly on managerial, staff, or policy perspectives. However, comprehensive studies examining the interplay between these elements are lacking. To address this gap, a study was conducted at Kakamega County Referral Hospital in Kenya, targeting the determinants affecting patient safety within critical care teams. Using an analytical cross-sectional design, the research included all healthcare providers in the Critical Care Units (CCUs). Data were collected via a self-administered questionnaire, which was analyzed using SPSS version 21. The questionnaire comprised eight sections, assessing healthcare professionals’ perceptions of patient safety. The study summarized demographic variables such as age, gender, and years of experience, with descriptive statistics. Inferential analyses, including chi-square tests, evaluated perception variations between different professional groups, particularly nurses and doctors. Multivariate regression analyses explored the relationship between perceived safety factors and overall safety perceptions. Findings revealed a wide range of confidence levels among healthcare professionals regarding existing patient safety protocols. While some noted improvements, others pointed out substantial gaps. Demographic factors, particularly years of experience and education level, significantly influenced safety perceptions. Key issues affecting these perceptions included inadequate staffing, resource challenges, and the implementation of non-punitive error reporting systems. Identified barriers were communication failures, insufficient training on safety protocols, and systemic operational challenges within the hospital. The study highlighted the urgent need for improved training programs, enhanced communication strategies, and the cultivation of an organizational culture that promotes transparency around safety issues. A correlation was established between healthcare professionals’ perceptions and measurable patient safety outcomes, such as incident reporting and adverse events. These insights can inform policy changes and practice improvements to enhance patient care. The recommendations stress the importance of healthcare systems prioritizing training on communication, teamwork, and error management; fostering a non-punitive culture for transparent error reporting; and optimizing resource allocation to resolve staffing issues. Strengthening interdepartmental communication through standardized protocols and regular evaluations, including staff feedback, is vital for ongoing improvement. Future research should focus on gender disparities in safety perceptions, organizational culture influence, training intervention effectiveness, long-term impacts of such interventions, comparative studies across various healthcare settings, and incorporating patient perspectives to drive significant safety enhancements.
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    ntegration of Critical Care Nurses in Antimicrobial Stewardship; Opportunities and Barriers at Thika Level 5 Hospital, Kiambu County, Kenya
    (Kenyatta University, 2025-05) Chege, Joseph Waithanji
    Antimicrobial stewardship optimizes appropriate use of antimicrobials through agent selection, route, dosing, and duration of therapy. It serves to optimize clinical outcomes of patients and limit adverse reactions of antimicrobials. Nurses are frontline implementers of antimicrobial stewardship. However, they face issues on inter-professional jurisdiction, hierarchical power relations within hospitals and limited training on antimicrobial stewardship. The main objective of this study is to explore the integration of nurses into antimicrobial stewardship activities in the critical care unit at Thika Level 5 Hospital. TL5H was selected for this study due to the availability of an antimicrobial stewardship program whose implementation suffers a disconnect among healthcare providers. The study used exploratory descriptive qualitative research design. Data collection was done through semi-structured interviews and NVIVO 14 software was used for thematic analysis of data. A total of 11 nurses working in the critical care unit were purposively selected and interviewed. Patient advocacy, communication and collaboration, monitoring and documenting, and patient education and empowerment emerged as important roles that nurses play in antimicrobial stewardship. Participants highlighted continuous medical education, inclusion of antimicrobial stewardship in formal nursing education, team work and organization support as major facilitators of nurses’ roles in antimicrobial stewardship. The study findings revealed that stringent regulatory requirements, heavy workload, poorly regulated systems and limited knowledge on antimicrobial stewardship as the major barriers that limit nurses’ role in antimicrobial stewardship. Education, teamwork, open communication and organizational support increase nurses’ awareness of AMS and ensures a coordinated approach in its implementation. Nurses’ inputs in decision making process on treatment plans and antimicrobial use is invaluable in promoting judicious use of antimicrobials. Future research should focus on redefining the nature, scope and influence of perceived nurses’ role in antimicrobial stewardship.
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    Nurses’ Perception of the Quality of Patient Care in Selected County Hospital Critical Care Units in Kenya
    (Kenyatta University, 2023-05) Mulinge, Kelvin
    The global Intensive Care Units (ICUs) perception of quality of care remains below :\e:;?‘g:t\]:u:czz:; ]l:(?ca:ors such as highv mor?a.lity and high infection rates been reported 9 | gical advancements in critical care medicine. Studies have reported ;‘:::;:‘;:“:: :::011;;31!::6 1;1;rses anld the institutior} to havcf. a profound impact on the i perspectiveci) ” y]‘ car'e the Patlent rece.lvfs. This study assessed the CCU S quality patient care, the association between nurses’ characteristics and the perception of patient care, the association between institutional characteristics and perception of patient care and the predictors of the perception of care in selected hospitals critical care units in Kenya. The study was a correlational study that’s used stratified sampling and census sampling to collect data. Over a 6-month period between May and December 2021, a questionnaire named, nurses’ perception of the quality of patient care in selected county hospital critical care units in Kenya was distributed to 103 nurses in Machakos, Embu, Muranga and Nyeri CCUs. The study findings revealed that one third (33%)of the nurses rated the quality of care as good while the rest two thirds (67%) rated the quality of care in their unit as fair or poor. Test for association (Chisquare) was conducted to investigate demographic characteristics and nurses’ perception of quality of patient care and revealed that years worked in ICU (p<0.001), specialization in CCU (p=0.023) and © sadre (p<0.001) were significantly associated with the nurses’ perception of quality patient care. In investigating the association between institutional characteristics and the nurses’ perception of quality patient care provided using chi-square, the findings revealed that all institutional factors assessed were significantly associated with the nurses’ perception of quality patient care .(pfoAOOI) apart from multidisciplinary teamwork in the unit where there was no assocm.tlon f.ound (] =0.253). Regression analysis revealed that determinants like: years of experience in CCU, specialized in CCU, adherence to aseptic procedure, moisture and incontinence checks t resources were independently associated with the and availability of VAP managemen , . nurses’ perception of quality patient care. This study concluded that nurses perceptions of quality of patient care in selected critical care units was below average and was greatly i ializati rsing cadre and institutional influenced by nurses’ experience, specialization, nursing characteristics.
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    Correlates associated with Adherence among Female Sex Workers on HIV pre-Exposure Prophylaxis in Nairobi City County, Kenya
    (Kenyatta University, 2024-03) Litiema, Edith Amahwa
    ::LC:C‘>§p?§llrg _prophylaxls (PrEP) is the use of ante-retroviral drug to prevent HIV .L,n ive lndmlduals who are at risk of acquiring HIV from becoming infected with HIV. l_’lEP use requires one to commit to taking the drug every day. The effectiveness of PrEP is conclalgd to adherence to regular uptake of medication. Barriers to good adherence should be identified and strategies to enhance adherence to PrEP be implemented. Female sex workers (FSW) are a susceptible group, and they face higher risk of HIV infections. Truvadz'a, a recommended drug for PrEP contains Tenofovir and emtricitabine. It is a nonnucleotides reverse transcriptase inhibitor (NRTI) that inhibits viral replications in the body, thus limiting number of HIV infected cells. The key objective of this study was to measure correlates for adherence in HIV negative Female Sex Workers to PrEP. This was accomplished by assessing the levels of knowledge about PrEP, evaluating adherence levels, examining factors influencing adherence, and analyzing strategies to improve PrEP adherence. A cross-sectional study design employing a mixed-method approach, incorporating both qualitative and quantitative data collection methods, was conducted from March to May 2021. The study enrolled 345 female sex workers (FSWs). Among them, 72% were unfamiliar with the name of PrEP, 39% reported missing PrEP doses, and 33% acknowledged missing appointments for PrEP refill. Qualitative data indicated a recommendation for monthly PrEP engagement meetings to bolster adherence. The research helped in identifying the need for clinical trials to test new products such as long acting injectable and monthly PrEP pills. This will reduce barriers to adherence thus enhancing HIV prevention.
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    Experiences of Mothers of Neonates Born with Gastroschisis in the Neonatal Intensive Care Unit at Kenyatta National Hospital: A PhenomeHlogical Study
    (Kenyatta university, 2023-11) Thaiya , Rosemary Muthoni
    The researcher carried out research on experiences of mothers with neonates born with gastroschisis in Kenyatta National Hospital and admitted in Neonatal Intensive Care Unit. The research focused on the lived experiences of mothers with neonates born with gastroschisis, the mental symptoms given by the mothers and the support needed by these mothers.The study employed phenomenological descriptive research design. The study assessed mothers whose neonates were admitted was conducted in the NICU at Kenyatta National Hospital. Purposive sampling technique was used to interview twenty-five (25) mothers. Primary data was collected using the semi-structured interview guide. The refined qualitative data was manually analysed. Data collected was transcribed verbatim and coded using structured code book. Thematic analysis was done inductively. The collected data was then developed into themes and subthemes then analysed.Data was presented using tables. The research indicated that mothers were positive about their pregnancies and attended antenatal clinics, mental symptoms exhibited by these mothers due to the nature of the neonates and the kind of support they needed from family and health care providers. The study found that there was both positive and negative relationship between mothers and healthcare providers. It was also found that mental symptoms led to fatigue. The study found that mothers experienced support from spouses, family members, health care givers and peers.The study concluded Prenatal Experiences of Mothers with neonates with gastroschisis was positive and majority of them were happy that they were pregnant and were ready to follow doctors' guidelines throughout the period. Postnatally, the mothers experienced various mental challenges due to inadequate support from close family members and inadequate information about the condition before their children were born. They too were unprepared to deal with the stress and difficulties related to the children's disease. Majority of the mothers received support from the family members and fellow mothers with similar experiencesA more thorough prenatal screening is recommended to assist in the early detection of such congenital disorders, which can direct birth preparations for the mother and child.Healthcare providers should consider the mental health of the mothers with neonates born with congenital anomalies other than concentrating on the neonates alone.To assist in easing the mental and emotional strain placedspit on parents, hoal staff should provide professional counselling. They should also encourage peer counselling from among mothers.
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    Determinants of Quality of Hemodialysis Services in Selected County Dialysis Centers in Nyanza Region, Kenya
    (Kenyatta University, 2024-05) Nyabaro, Doreen
    Background: Hemodialysis is a common management intervention in patients with Chronic Kidney Disease and End-Stage Renal Disease. Globally, there are approximately 1 billion renal patients on hemodialysis. Despite the increase in utilization of maintenance hemodialysis in low- and medium-income countries, there have been fewer efforts to assess the quality of hemodialysis services. Thus, there is a need to assess the quality of hemodialysis services. Objective: To evaluate the quality of hemodialysis services at selected county dialysis centers. Methodology: The study was a cross-section descriptive study. The study adopted a census method where 118 hemodialysis patients was considered. The participants were sampled consecutively based on the inclusion criteria. SERV-QUAL tool was used to measure perceived quality of hemodialysis services. Chi squares test for the association was used to determine the association between the patient, institutional factors, healthcare professional factors, and the quality of Hemodialysis services. Binary logistic regression analysis was used to determine predictors of quality hemodialysis services. Statistical Package for Social Sciences (SPSS version 26) was used for data analysis. Results: Majority of the patients 61.9%(n =73)were male, with 28.8%(n =34) of the respondents being aged 60 years and above. The findings further showed that 44.1% of the participants had secondary level education. The perceived quality of hemodialysis services was moderate with 56%. Bivariate analysis revealed that gender, level of education, presence of comorbidities, admission due to side effects, receiving social support, waiting time, receiving education before dialysis session and satisfaction with care were associated with quality of hemodialysis services. Multivariate analysis using logistic regression established that being male (AOR =3.75, 95%CI: 1.11 – 12.64, p =0.033), having secondary level education (AOR =2.31, 95%CI: 1.41 – 4.97, p =0.046), having been admitted due to side effects since the beginning of hemodialysis sessions (AOR =0.22, 95%CI:0.15 – 0.86, p<0.001), having received social support from family and friends (AOR =11.49, 95%CI: 1.79 -73.95, p =0.010) and not waiting longer to be allocated a HD (AOR = 0.21, 95%CI: 0.05 – 0.93, p =0.041) were significant predictors of perceived good quality of hemodialysis services: Conclusion and recommendation: The perceived quality of hemodialysis services remains moderate. Gender, education level, admission due to side effects waiting time and receiving social have been identified as predictors of perceived quality of hemodialysis services. Therefore, increased health education, training more staff on the needs of patients and reviewing appointment period based on the number of machines available is essential to improved care.
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    Determinants of Chronic Kidney Disease among Type 2 Diabetes Mellitus Patients at Gatundu Level 5 Hospital, Kiambu County, Kenya
    (Kenyatta University, 2023-12) Mwega, Bernard
    The prevalence of chronic kidney disease (CKD) is rising throughout the world, and it is one of the major public health menaces due to the significant morbidity and mortality it is associated with. The burden of CKD inexplicably affects low-income nations like Kenya, where the two main public health concerns responsible for the growing prevalence of CKD are hypertension and diabetes mellitus. The aim of this study was to assess the determinants of chronic kidney disease among type 2 diabetes mellitus patients. A hospital-based cross-sectional study design was conducted at Gatundu level 5 Hospital in Kiambu County, central Kenya, among adult (≥18 years) diabetes mellitus patients. Sample size was determined using Yamane Taro formula. Informed written consent was obtained from each participant and data was collected by interview and chart review. Glomerular filtration rate (GFR) was estimated from serum creatinine using modification of diet in renal disease (MDRD) formula, while CKD was defined as estimated GFR (eGFR) of less than 60mls/min/1.73m2 for more than three months. Multivariate logistic regression was used to identify independent determinants of CKD and a p-value of <0.05 was considered statistically significant. Majority of the participants (43.42%) were aged between 50-60 years and 95 (62.5%) of them were female. The researcher found out low level of patient awareness (25.8%) and high prevalence of CKD (78.2%). Factors associated with chronic kidney disease were gender, high blood pressure, type 2 diabetes mellitus, smoking, family history of CKD, obesity, poor knowledge of CKD and long duration of hypertension. The researcher observed a high prevalence rate of CKD amomg diabetic patients and hence recommended that the National and County Governments‟ Department of Health should take measures to increase the awareness about CKD prevention among high risk populations such as patients with diabetic mellitus.
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    Unmet Palliative Care Needs of Patients on Maintenance Hemodialysis at Thika Level 5 Hospital, Kiambu County, Kenya
    (Kenyatta University, 2024-06) Githuku, Stephen. N
    Globally, a huge gap exists between the required and the available renal palliative care services. The gap is particularly worse in low-and-medium income countries despite having the highest percentage of patients requiring palliative care. Maintenance hemodialysis patients contribute a sizable percentage of the global renal patient population in need of palliative care. Successful provision of adequate palliative care services requires a holistic understanding of the patients’ needs. In Kenya, however, data on palliative care needs of patients on maintenance hemodialysis is limited. This study was conducted to explore the unmet palliative care needs of patients on maintenance hemodialysis at Thika Level 5 Hospital, Kiambu County. The specific objectives of the study were to assess the physical, psychological and social palliative care needs of patients on maintenance hemodialysis and identify the patient related barriers to meeting these needs. A descriptive qualitative study anchored by the 6-S model for person centered palliative care was conducted using twelve purposively sampled patients on maintenance hemodialysis at Thika Level 5 Hospital’s renal unit. Participants in the study were 18 years and above, had been receiving maintenance hemodialysis therapy at the renal unit for more than six months and could speak either English or Kiswahili. Those with cognitive impairment, critical illness and had undergone kidney transplantation were excluded. Data collection was done using semi-structured audiotaped interviews which lasted between 30-45 minutes. An interview guide based on the Integrated Palliative Outcome Score (IPOS) renal survey was used to conduct the interviews. Data collection was done until saturation was reached. The recorded interviews were transcribed verbatim and analyzed using thematic analysis. NVIVO 14 qualitative data analysis software was used to analyze the data. The six general principles of thematic analysis including familiarizing with the data set, initial generation of codes, searching for themes, reviewing themes, defining and naming themes and producing the report were used to guide the process. Ethical approval to conduct the study was obtained from Kenyatta University Graduate School, Kenyatta University Ethics and Review Committee (KUERC), the National Commission for Science, Technology and Innovation (NACOSTI), County Government of Kiambu and Thika Level 5 Hospital Training, Research and Ethics Committee (TREC). Eight major themes including distressing physical symptoms, difficult thoughts, interrupted relationships, financial burden on the family, abandonment by friends, spiritual coping and barriers to palliative care emerged from the data analysis. Also, eleven sub-themes including fatigue, fluctuations in appetite, skin changes, uncertainty about the future, stress and worry, inability to get more children, caregiver burden, prayers, material support, lack of knowledge and fear of being judged were identified. This study reports that patients on maintenance hemodialysis experience numerous unmet palliative care needs. The needs regard to physical, psychological and social aspects. Also, lack of knowledge on palliative care is the primary patient related barrier to meeting palliative care needs. The study underscores that the provision of timely, specific and adequate palliative care is needed to enhance the coping and survival of patients on maintenance hemodialysis. Furthermore, the study urges more strategies to be put in place to ensure patients on maintenance hemodialysis and their families are well educated on renal palliative care.
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    Uptake of Chronic Kidney Disease Preventive Practices Among Diabetic and Hypertensive Patients at the Nyeri County Referral Hospital, Kenya
    (Kenyatta University, 2024-02) Wakhungu, Liner
    Chronic kidney disease (CKD) has been ranked as the 17th top cause of worldwide years loss of life and a key cause of deaths rising at a fast rate, having increased by 31.7% from 2005 to 2015. Patients with hypertension and diabetes are at a higher risk of developing CKD. The study objective was to establish the factors that influence CKD preventive practices among diabetes and hypertension patients at Nyeri County Referral Hospital (NCRH). Data was obtained from 190 participants by the use of a questionnaire. Data was analyzed using SPSS and presented using descriptive statistics. Chi-square was used to test for association among variables while logistic regression analysis was used to test for the predictors of CKD prevention uptake. From the findings, 84.2% of the participants had good CKD prevention uptake. Gender  2 (1) = 6.243, p= .012 age  2 (4) = 13.146, p= .011, and income  2 (4) = 25.467, p <0.001 were significantly associated with CKD preventive practice uptake. Health care provider communicating to DM/HTN patients in a language they could understand  2 (2) = 18.102, p<0.001, accessing all the laboratory services within the hospital  2 (2) = 8.469, p=.014 and being able to obtain the prescribed drugs from the hospital pharmacy  2 (2) = 6.361, p=.043 were significantly associated with CKD prevention uptake. The predictors for CKD prevention uptake included gender, income, age, and being well informed about the disease condition. In conclusion the study participants had good CKD prevention practices uptake. Communication with health care providers, accessibility of laboratory services and being informed of the disease conditions influence uptake of CKD. The study recommends that health care providers in Nyeri County Referral Hospital should provide CKD prevention health education program especially to the at-risk population. The health care services should also be made accessible, available and affordable to diabetic and hypertensive patients.
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    Psychosocial Burden and Its Determinants among Caregivers of Children with Colostomy at Kenyatta National Hospital, Nairobi City County Kenya
    (Kenyatta University, 2023-06) Ronoh, Lilian Chebet; Grace Githemo; Sarah Tai
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    Determinants of Kidney Transplantation Uptake among Patients with End Stage Kidney Disease on Haemodialysis at Selected National Referral Hospitals in Kenya
    (Kenyatta University, 2023-05) Nduati, Joseph Mwororo; Joseph Nduati; Grace Githemo
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    Stressors and Coping Strategies among Women Breast Cancer Survivors at Kenyatta National Hospital, Nairobi City County, Kenya
    (Kenyatta University, 2023-11) Chege, Kuria Patrick; Grace Githemo; Nelson Menza
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    Determinants of the Quality of Life of Caregivers of Children with Sickle Cell Disease at Siaya County Referral Hospital, Kenya
    (Kenyatta University, 2023-07) Okinyi, Joash; Sarah Bett; Grace Githemo
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    Nursing Handover Experiences and Perspectives in the Critical Care Unit at Murang’a County Referral Hospital, Kenya
    (Kenyatta University, 2023-11) Murigi, Mwangi; Nickcy Mbuthia; Lucy Meng’anyi
    Continuity in delivery of nursing care to patient in the critical care unit is of utmost importance. To achieve this consistency, nurses engage in a process of transfer of patients’ clinical information in the form of nursing handover, The adoption of various handover procedures result in variation of the information exchanged. In the critical care unit, the intricacy of the patient condition compounded by the advanced patient monitoring translates into a more complex nature of the nursing handover. Despite the existence of handover guidelines and formats, gaps have been detected regarding the contents of the handover and its effects on the continuity of care. The focus of the study was to explore the experiences and perspectives of nurses with nursing handover in the critical care unit. To realize the aim of the proposed study, a phenomenological qualitative design was adopted while utilizing a deductive approach. Indepth interviews were carried out on nine critical care nurses from the Murang’a County Referral Hospital after obtaining ethical approval from relevant institutions. Thematic analysis was done manually for the qualitative data. The study results showed that critical care nurses believed they were individually equipped with adequate knowledge to carry out effective departmental and interdepartmental handover. The existence of handover policies in the critical care unit was considered a major enabler of the handover. They also believed that strained human resource, lack of standardized handover tools and deviation from the set handover rules negatively impacted the handover process. Furthermore, they reported perceived insufficiency in the management’s role in handover evaluation and feedback. Moreover, all participants advocated for improvement of the current handover practices for improved quality of patient care as well as sense of self-accomplishment among the nurses. There are pertinent implications in the findings of this research for critical care nurses, nurses in other departments and policy makers. Based on the study findings the handover process would benefit from enhanced adherence to the existing handover policies. Handover training targeting nurses in other departments would promote communication of patient information between critical care unit and other departments. Periodic audits of the handover documentation and process with subsequent feedback would be acontrol for evaluation of the handover. Further, addressing scarcity of resources and implementing the nurses’ perceived strategies would ensure a seamless handover
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    Compliance with Hemodialysis Treatment among End Stagekidney Disease Patients in Nyeri County, Kenya.
    (Kenyatta University, 2022) Chege, Jacinta Wanjiku; Grace Githemo; Lister Onsongo
    The number of End Stage Kidney Disease (ESKD) patients on hemodialysis (HD) globally has become a public health concern. Compliance with hemodialysis recommendation aids to improve health outcomes and prevent complications. However, non-compliance to hemodialysis among ESKD patients has been a major problem. The purpose of the study was aimed at describing the level of compliance with hemodialysis and the associated factors among ESKD patients in three selected dialysis centers in Nyeri County. A descriptive cross-sectional study, utilizing quantitative research method and targeting 80 participants was done. Census method was used to recruit the study participants. Data was collected through administration of a questionnaire and analyzed by use of computer software, statistical package for the social science (SPSS) version 24. Descriptive statistics was used to determine the level of compliance to hemodialysis. Inferential statistics was used to determine factors associated with compliance to hemodialysis. SPSS version 24 was used in data analysis.The study findings revealed that compliance with hemodialysis treatment was 53%. The findings showed that there was significant association between compliance and; marital status, x2 (2, N=30) = 5.151, p =0.029, income, x2 (4, N=12) = 11.322, p =0.045, and number of hospital admissions, x2 (3, N=I) = 38.069, p =0.0001. Shortened hemodialysis,(aOR = 5.5, p = 0.002) and waiting time for two hours prior to start their hemodialysis session (aOR =4.11, p =0.005) were independent predictors of noncompliance with hemodialysis treatment.Despite opening new hemodialysis centers in Nyeri County to increase availability and accessibility of hemodialysis services, compliance still remains a major challenge among patients. Shortening of hemodialysis sessions, low economic status, inadequate machines and failure to repair machines when they break down were major barriers to hemodialysis compliance. Therefore, adequate resource allocation should be considered when opening new hemodialysis centers.