Determinants of Chronic Kidney Disease among Type 2 Diabetes Mellitus Patients at Gatundu Level 5 Hospital, Kiambu County, Kenya
Loading...
Date
2023-12
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Kenyatta University
Abstract
The prevalence of chronic kidney disease (CKD) is rising throughout the world, and it
is one of the major public health menaces due to the significant morbidity and
mortality it is associated with. The burden of CKD inexplicably affects low-income
nations like Kenya, where the two main public health concerns responsible for the
growing prevalence of CKD are hypertension and diabetes mellitus. The aim of this
study was to assess the determinants of chronic kidney disease among type 2 diabetes
mellitus patients. A hospital-based cross-sectional study design was conducted at
Gatundu level 5 Hospital in Kiambu County, central Kenya, among adult (≥18 years)
diabetes mellitus patients. Sample size was determined using Yamane Taro formula.
Informed written consent was obtained from each participant and data was collected
by interview and chart review. Glomerular filtration rate (GFR) was estimated from
serum creatinine using modification of diet in renal disease (MDRD) formula, while
CKD was defined as estimated GFR (eGFR) of less than 60mls/min/1.73m2
for more
than three months. Multivariate logistic regression was used to identify independent
determinants of CKD and a p-value of <0.05 was considered statistically significant.
Majority of the participants (43.42%) were aged between 50-60 years and 95 (62.5%)
of them were female. The researcher found out low level of patient awareness
(25.8%) and high prevalence of CKD (78.2%). Factors associated with chronic kidney
disease were gender, high blood pressure, type 2 diabetes mellitus, smoking, family
history of CKD, obesity, poor knowledge of CKD and long duration of hypertension.
The researcher observed a high prevalence rate of CKD amomg diabetic patients and
hence recommended that the National and County Governments‟ Department of
Health should take measures to increase the awareness about CKD prevention among
high risk populations such as patients with diabetic mellitus.
Description
A Research Thesis Submitted in Partial Fulfilment of the Requirement for the Award of the Degree of Master of Science in Nursing (Nephrology), Kenyatta University, December 2023