In Vitro Anti-Acetylcholinesterase Activity of Crude Fruits Sap Extract of Solanum incanum in Green Peach Aphids

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dc.contributor.authorUmar, A.
dc.contributor.authorMgutu, A.J.
dc.contributor.authorPiero, N.M.
dc.contributor.authorNjoroge, A.W.
dc.contributor.authorNjoroge, G.S.
dc.contributor.authorMaina, M.B.
dc.contributor.authorMuriithi, N.J.
dc.contributor.authorKiambi, M.J.
dc.contributor.authorMutero, N.G.
dc.contributor.authorMwonjoria, J.K.
dc.date.accessioned2015-12-01T08:05:31Z
dc.date.available2015-12-01T08:05:31Z
dc.date.issued2015
dc.descriptionDOI:10.4172/2329-6631.1000142en_US
dc.description.abstractAcetylcholinesterase is a key enzyme that terminates nerve impulses by catalyzing the hydrolysis of neurotransmitter, acetylcholine, in the nervous system in various organisms. Irreversible inhibitors have been developed as insecticides such as organophosphates and carbamates. Aqueous crude fruit sap extract of S. incanum was evaluated for acetylcholinesterase activity in green peach aphids using Ellman’s method and is found active in inhibiting the ACHe of green peach aphids. All tested concentrations of crude fruits sap extract of S. incanum possessed the ability to inhibit acetylcholinesterase of green peach aphids at dose dependent manner and IC50 of 49.9 was calculated. This study suggest that aqueous crude fruit sap extract of S. incanum inhibit the acetylcholinesterase of the green peach aphids and it is possible the extract has compounds that increase both the level and duration of the neurotransmitter action.en_US
dc.identifier.issn2329-6631
dc.identifier.urihttp://ir-library.ku.ac.ke/handle/123456789/13925
dc.language.isoenen_US
dc.publisherOMICS Internationalen_US
dc.subjectAcetylcholinesteraseen_US
dc.subjectSolanum incanumen_US
dc.subjectGreen peach aphidsen_US
dc.subjectOrganophosphatesen_US
dc.titleIn Vitro Anti-Acetylcholinesterase Activity of Crude Fruits Sap Extract of Solanum incanum in Green Peach Aphidsen_US
dc.typeArticleen_US
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