RP-Department of Medical Physiology
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Recent Submissions
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Factors Effecting Quality Of Life for Family Caregivers of Cancer Patients in Kenya
(2022): Characteristics, including age, educational level, economics, and geographical setting during care provision significantly affect quality of life (QoL) among cancer patient caregivers in high-income countries. Investigation ... -
Determinants of Sexual Function among Survivors of Gynaecological Cancers in a Tertiary Hospital: A Cross-Sectional Study
(ecancer Global Foundation, 2022)Background: Gynaecological cancer impacts approximately three million women globally. The problem is much more intense in resource-limited countries. Sexual health is a critical aspect of gynaecological cancer treatment ... -
The Ethical and Validity Conundrum in Epilepsy Research in LMIC Settings
(Frontiers, 2023)In the last few decades, research in epilepsy has significantly improved understanding of risk factors and etiologies associated with epilepsy, promoting greater access to interventions and medications that have improved ... -
Risk Factors for Seizure Recurrence after Initial Withdrawal of Anti-Seizure Medications in Children with Epilepsy at Aga Khan University Hospital, Nairobi, Kenya.
(Elsevier Inc, 2023)We sought to determine risk factors associated with seizure recurrence following initial withdrawal of anti-seizure medications (ASM) among children with epilepsy. Methods: This was a retrospective observational study of ... -
International League against Epilepsy Classification And Definition of Epilepsy Syndromes with Onset in Childhood: Position Paper by the ILAE Task Force on Nosology and Definitions
(Wiley online library, 2022-03)The 2017 International League Against Epilepsy classification has defined a three-tier system with epilepsy syndrome identification at the third level. Although a syndrome cannot be determined in all children with epilepsy, ... -
Quality Perspective of Healthcare Provision in Selected Public Health Facilities after Devolution in Garissa County.
(International Academic Journals, 2021)Devolution is delegation of power, governance and resources from centralized government to local/subnational level jurisdictions. The Kenyan constitution allows two levels of government i.e. the national and county levels ... -
Baseline Blood Count Levels Increase Odds Of Cytopenia among CML Patients in Kenya: A Case Control Study
(Research square, 2021)Imatinib is the gold standard for the treatment of all phases of Philadelphia positive Chronic Myeloid Leukemia (CML). During treatment, patients may develop cytopenia. We aimed to study the baseline characteristics and ... -
Dyslipidemia in blood pressure control among adult hypertensive patients in Kiambu County Hospital Kenya
(The East and Central Africa Medical Journal, 2020)Introduction: Hypertension is one of the most common non-communicable diseases with about 40% global prevalence in adults and 46% in Africa. Dyslipidemia, among other factors may lead to poor blood pressure control in ... -
Streptococcus pneumoniae serotype epidemiology among PCV-10 vaccinated and unvaccinated children at Gertrude’s Children’s Hospital, Nairobi County: a cross-sectional study
(F1000Research, 2018)Background: Streptococcus pneumoniae (SPn) serotype replacement and emergence of multidrug resistant SPn has exacerbated the need for continuous regional serotype surveillance. We investigated SPn serotypes circulating among ... -
Metabolic syndrome and its components among university students in Kenya
(BioMed Central, 2017)Background: Metabolic syndrome refers to a cluster of interrelated disorders which occur together causing an increase in the risk of developing cardiovascular disease and diabetes. The university population is an ... -
Key bottlenecks to the provision of safe obstetric anaesthesia in low- income countries; a cross-sectional survey of 64 hospitals in Uganda
(BioMed Central, 2017)Background: Despite recent advances in surgery and anaesthesia which significantly improve safety, many health facilities in low-and middle-income countries (LMICs) remain chronically under-resourced with inability to ... -
Early management of traumatic brain injury in a Tertiary hospital in Central Kenya: A clinical audit
(Medknow Publications, 2016)Background: Traumatic brain injury (TBI) is a major cause of death and disability worldwide and is mostly attributed to road traffic accidents in resource‑poor areas. However, access to neurosurgical care is poor in ... -
Acne vulgaris in general population of rural western Kenya: cross-sectional community survey
(International Society of Dermatology, 2015) -
Crypotococcal meningitis in a none-HIV infected five month old infant with rickets: Case report
(Kenyatta University, 2015-08)Crypotococcal is an invasive fungal disease, now endemic in the tropics. It is largely transmitted through inhalation, but can be transmitted locally through skin and eyes. Mostly, it causes disease in immune compromised ... -
Antimicrobial resistance patterns among E. coli isolates from children presenting with diarrhoea at a cosmopolitan hospital in Kenya
(Kenyatta University, 2015-08)Diarrhoea is a serious infection that kills at least 2 million children globally. Children under the age of 5 years are particularly predisposed to diarrhoea especially if the surrounding environment is contaminated or ...
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Factors Effecting Quality Of Life for Family Caregivers of Cancer Patients in Kenya
(2022): Characteristics, including age, educational level, economics, and geographical setting during care provision significantly affect quality of life (QoL) among cancer patient caregivers in high-income countries. Investigation ... -
Determinants of Sexual Function among Survivors of Gynaecological Cancers in a Tertiary Hospital: A Cross-Sectional Study
(ecancer Global Foundation, 2022)Background: Gynaecological cancer impacts approximately three million women globally. The problem is much more intense in resource-limited countries. Sexual health is a critical aspect of gynaecological cancer treatment ... -
The Ethical and Validity Conundrum in Epilepsy Research in LMIC Settings
(Frontiers, 2023)In the last few decades, research in epilepsy has significantly improved understanding of risk factors and etiologies associated with epilepsy, promoting greater access to interventions and medications that have improved ... -
Risk Factors for Seizure Recurrence after Initial Withdrawal of Anti-Seizure Medications in Children with Epilepsy at Aga Khan University Hospital, Nairobi, Kenya.
(Elsevier Inc, 2023)We sought to determine risk factors associated with seizure recurrence following initial withdrawal of anti-seizure medications (ASM) among children with epilepsy. Methods: This was a retrospective observational study of ... -
International League against Epilepsy Classification And Definition of Epilepsy Syndromes with Onset in Childhood: Position Paper by the ILAE Task Force on Nosology and Definitions
(Wiley online library, 2022-03)The 2017 International League Against Epilepsy classification has defined a three-tier system with epilepsy syndrome identification at the third level. Although a syndrome cannot be determined in all children with epilepsy, ... -
Quality Perspective of Healthcare Provision in Selected Public Health Facilities after Devolution in Garissa County.
(International Academic Journals, 2021)Devolution is delegation of power, governance and resources from centralized government to local/subnational level jurisdictions. The Kenyan constitution allows two levels of government i.e. the national and county levels ... -
Baseline Blood Count Levels Increase Odds Of Cytopenia among CML Patients in Kenya: A Case Control Study
(Research square, 2021)Imatinib is the gold standard for the treatment of all phases of Philadelphia positive Chronic Myeloid Leukemia (CML). During treatment, patients may develop cytopenia. We aimed to study the baseline characteristics and ... -
Dyslipidemia in blood pressure control among adult hypertensive patients in Kiambu County Hospital Kenya
(The East and Central Africa Medical Journal, 2020)Introduction: Hypertension is one of the most common non-communicable diseases with about 40% global prevalence in adults and 46% in Africa. Dyslipidemia, among other factors may lead to poor blood pressure control in ... -
Streptococcus pneumoniae serotype epidemiology among PCV-10 vaccinated and unvaccinated children at Gertrude’s Children’s Hospital, Nairobi County: a cross-sectional study
(F1000Research, 2018)Background: Streptococcus pneumoniae (SPn) serotype replacement and emergence of multidrug resistant SPn has exacerbated the need for continuous regional serotype surveillance. We investigated SPn serotypes circulating among ... -
Metabolic syndrome and its components among university students in Kenya
(BioMed Central, 2017)Background: Metabolic syndrome refers to a cluster of interrelated disorders which occur together causing an increase in the risk of developing cardiovascular disease and diabetes. The university population is an ... -
Key bottlenecks to the provision of safe obstetric anaesthesia in low- income countries; a cross-sectional survey of 64 hospitals in Uganda
(BioMed Central, 2017)Background: Despite recent advances in surgery and anaesthesia which significantly improve safety, many health facilities in low-and middle-income countries (LMICs) remain chronically under-resourced with inability to ... -
Early management of traumatic brain injury in a Tertiary hospital in Central Kenya: A clinical audit
(Medknow Publications, 2016)Background: Traumatic brain injury (TBI) is a major cause of death and disability worldwide and is mostly attributed to road traffic accidents in resource‑poor areas. However, access to neurosurgical care is poor in ... -
Acne vulgaris in general population of rural western Kenya: cross-sectional community survey
(International Society of Dermatology, 2015) -
Crypotococcal meningitis in a none-HIV infected five month old infant with rickets: Case report
(Kenyatta University, 2015-08)Crypotococcal is an invasive fungal disease, now endemic in the tropics. It is largely transmitted through inhalation, but can be transmitted locally through skin and eyes. Mostly, it causes disease in immune compromised ... -
Antimicrobial resistance patterns among E. coli isolates from children presenting with diarrhoea at a cosmopolitan hospital in Kenya
(Kenyatta University, 2015-08)Diarrhoea is a serious infection that kills at least 2 million children globally. Children under the age of 5 years are particularly predisposed to diarrhoea especially if the surrounding environment is contaminated or ... -
Abnormal Intra-aural Pressure Waves Associated with Death in African Children with acute Nontraumatic Coma.
(Nature Publishing Group, 2015)BACKGROUND: We explored the relationship between tympanic membrane displacement (TMD) measurements, a tool to monitor intracranial pressure noninvasively, and clinical features and death in children with acute coma in ... -
Neonatal seizures in a rural Kenyan District Hospital: aetiology, incidence and outcome of hospitalization
(BioMed Central, 2010-03)Background: Acute seizures are common among children admitted to hospitals in resource poor countries. However, there is little data on the burden, causes and outcome of neonatal seizures in sub-Saharan Africa. We ... -
Iron deficiency and acute seizures: results from children living in rural Kenya and a meta-analysis.
(Public Library of Science, 2010-11)Background: There are conflicting reports on whether iron deficiency changes susceptibility to seizures. We examined the hypothesis that iron deficiency is associated with an increased risk of acute seizures in children ... -
Clinical stroke scores for distinguishing stroke subtypes: a systematic review of diagnostic test accuracy
(2013-04)Background Stroke is a major cause of morbidity and mortality especially in low and middle income countries. Computerized tomography is used to distinguish between ischemic and hemorrhagic subtypes, but it is expensive ... -
Isolation and characterization of microsatellite markers in the newly discovered invasive fruit fly pest in Africa, Bactrocera invadens (Diptera: Tephritidae).
(Molecular Ecology Resources, 2008-11)We describe the isolation and characterization of 11 polymorphic microsatellite loci from the recently discovered fruit fly pest, Bactrocera invadens. The polymorphism of these loci was tested in individual flies from two ...
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