RP-Department of Biochemistry and Biotechnology
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Recent Submissions
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Absence of Molecular Evidence of Filovirus Circulating In Bats and Rodents in Laikipia North Sub-County, Kenya: A Cross Sectional Study
(https://www.one-health.panafrican-med-journal.com/content/article/7/34, 2022)In the recent decade, pathogenic zoonotic viruses have emerged in different geographical locations almost annually. These changes have led to new complex interactions between humans, animals and the environment, creating ... -
Arbuscular Mycorrhizal Fungi and Bradyrhizobium Co-Inoculation Enhances Nitrogen Fixation and Growth of Green Grams (Vigna Radiata L.) Under Water Stress
(JOURNAL OF PLANT NUTRITION, 2020)Green gram (Vigna radiata L. Wildzek) is a neglected crop with great potential to boost food security among small scale farmers. Inoculation of this crop with beneficial soil microbiota can sustainably improve its production ... -
Antioxidant, Anti-Inflammatory, Acute Oral Toxicity, and Qualitative Phytochemistry of The Aqueous Root Extract of Launaea cornuta (Hochst. Ex Oliv. & Hiern.)
(SAGE, 2021-06-26)The root and leaf extracts of Launaea cornuta have been locally used in traditional medicine for decades to manage inflammatory conditions and other oxidative-stress-related syndromes; however, their pharmacologic efficacy ... -
Contact Toxicity Effects of Selected Organic Leaf Extracts of Tithonia diversifolia (Hemsl.) A. Gray and Vernonia lasiopus (O. Hoffman) against Sitophilus zeamais Motschulsky (Coleoptera: Curculionidae)
(Hindawi, 2021)Maize weevil (Sitophilus zeamais) infestation results in a substantial reduction in the quantity and deterioration of the quality of stored maize. Most farmers control weevils using conventional pesticides which are usually ... -
Characterization of HIV-1 Integrase Gene and Resistance Associated Mutations Prior to Roll out of Integrase Inhibitors by Kenyan National HIV-Treatment Program in Kenya
(Jimma University, 2020)BACKGROUND: Antiretroviral therapy containing an integrase strand transfer inhibitor plus two Nucleoside Reverse Transcriptase inhibitors has now been recommended for treatment of HIV-1-infected patients. This thus determined ... -
Arbuscular Mycorrhizal Fungi and Bradyrhizobium Co-Inoculation Enhances Nitrogen Fixation and Growth of Green Grams (Vigna Radiata L.) Under Water Stress
(Taylor & Francis, 2020)Green gram (Vigna radiata L. Wildzek) is a neglected crop with great potential to boost food security among small scale farmers. Inoculation of this crop with beneficial soil microbiota can sustainably improve its ... -
Exposure to Chronic Dietary Aflatoxin Poisoning Is Potentially a Compromising Condition in COVID-19 Patients in Africa
(African Journal of Agriculture, Food, Nutrition and Development, 2021)In this time of COVID-19 pandemic, we draw attention to a potential aggravating risk factor in Kenya, one that is amenable to mitigation. Advanced age, male sex and underlying medical conditions [1,2] are the main risk ... -
Antinociceptive Potential of Methanol Leaf Extracts of Cissampelos Parreira (Linn), Lantana Camara (Linn) and Ocimum Gratissimum (African Basil)
(Bangladesh Society for Microbiology, Immunology, and Advanced Biotechnology (BSMIAB), 2021)The effects of Cissampelos pareira (Linn), Lantana camara (Linn) and Ocimum gratissimum (African basil) leaf extracts on pain have not been biologically determined despite their frequent traditional use in pain management. ... -
Human Immunodeficiency Virus Type 1 ((HIV-1) Subtypes in the Northwest Region, Cameroon
(BioMed Central, 2019)Background: The high genetic diversity of HIV-1 has been shown to influence the global distribution, disease progression, treatment success, and the development of an effective vaccine. Despite the low HIV prevalence ... -
Microbial Community Structure and Diversity in an Integrated System of Anaerobic-Aerobic Reactors and a Constructed Wetland for the Treatment of Tannery Wastewater in Modjo, Ethiopia
(PLOS ONE, 2014)A culture-independent approach was used to elucidate the microbial diversity and structure in the anaerobic-aerobic reactors integrated with a constructed wetland for the treatment of tannery wastewater in Modjo town, ... -
Gametocyte Clearance in Children, From Western Kenya, With Uncomplicated Plasmodium Falciparum Malaria after Artemether–Lumefantrine or Dihydroartemisinin–Piperaquine Treatment
(Malaria Journal, 2019)Background: The efcacy and safety of artemether–lumefantrine (AL) and dihydroartemisinin–piperaquine (DP) against asexual parasites population has been documented. However, the efect of these anti-malarials on sexual parasites ... -
Prevalence of Viral Severe Acute Respiratory Infections in Patients in the Intensive Care Unit and Those under Mechanical Ventilation in Moi Teaching and Referral Hospital, Uasin Gishu County, Kenya
(International Journal of Virology and Molecular Biology, 2018)Any nation must ensure that the prevalence and incidence of particular disease is kept in check and that the population is aware in case of an increase in incidences and prevalence of a particular disease. Viruses are ... -
Chemical Parameters and Bacterial Communities Associated with Larval Habitats of Anopheles, Culex and Aedes Mosquitoes (Diptera: Culicidae) in Western Kenya
(International Journal of Tropical Insect Science, 2016)Aquatic larval habitat conditions influence the development, fitness and vectorial capacity of mosquitoes. In turn, human activities can influence these conditions and shape mosquito vector distribution, thus affecting ... -
Dual African Origins of Global Aedes aegypti s.l. Populations Revealed by Mitochondrial DNA
(PLOS Neglected Tropical Diseases, 2013)Background: Aedes aegypti is the primary global vector to humans of yellow fever and dengue flaviviruses. Over the past 50 years, many population genetic studies have documented large genetic differences among global ... -
Efficient Shoot Organogenesis Using Leaf Disc and Nodal Explants of Passion Fruit (Passiflora edulis Sims) and Genetic Fidelity Assessment Using Sequence-Related Amplified Polymorphism (SRAP) Markers
(Hindawi International Journal of Agronomy, 2020)Passion fruit (Passiflora edulis (Sims)) is currently ranked third among fruit exports from Kenya and has great potential since the demand for both fresh fruit and processed juice is on a continuous increase. Passion fruit ...
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Absence of Molecular Evidence of Filovirus Circulating In Bats and Rodents in Laikipia North Sub-County, Kenya: A Cross Sectional Study
(https://www.one-health.panafrican-med-journal.com/content/article/7/34, 2022)In the recent decade, pathogenic zoonotic viruses have emerged in different geographical locations almost annually. These changes have led to new complex interactions between humans, animals and the environment, creating ... -
Arbuscular Mycorrhizal Fungi and Bradyrhizobium Co-Inoculation Enhances Nitrogen Fixation and Growth of Green Grams (Vigna Radiata L.) Under Water Stress
(JOURNAL OF PLANT NUTRITION, 2020)Green gram (Vigna radiata L. Wildzek) is a neglected crop with great potential to boost food security among small scale farmers. Inoculation of this crop with beneficial soil microbiota can sustainably improve its production ... -
Antioxidant, Anti-Inflammatory, Acute Oral Toxicity, and Qualitative Phytochemistry of The Aqueous Root Extract of Launaea cornuta (Hochst. Ex Oliv. & Hiern.)
(SAGE, 2021-06-26)The root and leaf extracts of Launaea cornuta have been locally used in traditional medicine for decades to manage inflammatory conditions and other oxidative-stress-related syndromes; however, their pharmacologic efficacy ... -
Contact Toxicity Effects of Selected Organic Leaf Extracts of Tithonia diversifolia (Hemsl.) A. Gray and Vernonia lasiopus (O. Hoffman) against Sitophilus zeamais Motschulsky (Coleoptera: Curculionidae)
(Hindawi, 2021)Maize weevil (Sitophilus zeamais) infestation results in a substantial reduction in the quantity and deterioration of the quality of stored maize. Most farmers control weevils using conventional pesticides which are usually ... -
Characterization of HIV-1 Integrase Gene and Resistance Associated Mutations Prior to Roll out of Integrase Inhibitors by Kenyan National HIV-Treatment Program in Kenya
(Jimma University, 2020)BACKGROUND: Antiretroviral therapy containing an integrase strand transfer inhibitor plus two Nucleoside Reverse Transcriptase inhibitors has now been recommended for treatment of HIV-1-infected patients. This thus determined ... -
Arbuscular Mycorrhizal Fungi and Bradyrhizobium Co-Inoculation Enhances Nitrogen Fixation and Growth of Green Grams (Vigna Radiata L.) Under Water Stress
(Taylor & Francis, 2020)Green gram (Vigna radiata L. Wildzek) is a neglected crop with great potential to boost food security among small scale farmers. Inoculation of this crop with beneficial soil microbiota can sustainably improve its ... -
Exposure to Chronic Dietary Aflatoxin Poisoning Is Potentially a Compromising Condition in COVID-19 Patients in Africa
(African Journal of Agriculture, Food, Nutrition and Development, 2021)In this time of COVID-19 pandemic, we draw attention to a potential aggravating risk factor in Kenya, one that is amenable to mitigation. Advanced age, male sex and underlying medical conditions [1,2] are the main risk ... -
Antinociceptive Potential of Methanol Leaf Extracts of Cissampelos Parreira (Linn), Lantana Camara (Linn) and Ocimum Gratissimum (African Basil)
(Bangladesh Society for Microbiology, Immunology, and Advanced Biotechnology (BSMIAB), 2021)The effects of Cissampelos pareira (Linn), Lantana camara (Linn) and Ocimum gratissimum (African basil) leaf extracts on pain have not been biologically determined despite their frequent traditional use in pain management. ... -
Human Immunodeficiency Virus Type 1 ((HIV-1) Subtypes in the Northwest Region, Cameroon
(BioMed Central, 2019)Background: The high genetic diversity of HIV-1 has been shown to influence the global distribution, disease progression, treatment success, and the development of an effective vaccine. Despite the low HIV prevalence ... -
Gametocyte Clearance in Children, From Western Kenya, With Uncomplicated Plasmodium Falciparum Malaria after Artemether–Lumefantrine or Dihydroartemisinin–Piperaquine Treatment
(Malaria Journal, 2019)Background: The efcacy and safety of artemether–lumefantrine (AL) and dihydroartemisinin–piperaquine (DP) against asexual parasites population has been documented. However, the efect of these anti-malarials on sexual parasites ... -
Prevalence of Viral Severe Acute Respiratory Infections in Patients in the Intensive Care Unit and Those under Mechanical Ventilation in Moi Teaching and Referral Hospital, Uasin Gishu County, Kenya
(International Journal of Virology and Molecular Biology, 2018)Any nation must ensure that the prevalence and incidence of particular disease is kept in check and that the population is aware in case of an increase in incidences and prevalence of a particular disease. Viruses are ... -
Microbial Community Structure and Diversity in an Integrated System of Anaerobic-Aerobic Reactors and a Constructed Wetland for the Treatment of Tannery Wastewater in Modjo, Ethiopia
(PLOS ONE, 2014)A culture-independent approach was used to elucidate the microbial diversity and structure in the anaerobic-aerobic reactors integrated with a constructed wetland for the treatment of tannery wastewater in Modjo town, ... -
Chemical Parameters and Bacterial Communities Associated with Larval Habitats of Anopheles, Culex and Aedes Mosquitoes (Diptera: Culicidae) in Western Kenya
(International Journal of Tropical Insect Science, 2016)Aquatic larval habitat conditions influence the development, fitness and vectorial capacity of mosquitoes. In turn, human activities can influence these conditions and shape mosquito vector distribution, thus affecting ... -
Dual African Origins of Global Aedes aegypti s.l. Populations Revealed by Mitochondrial DNA
(PLOS Neglected Tropical Diseases, 2013)Background: Aedes aegypti is the primary global vector to humans of yellow fever and dengue flaviviruses. Over the past 50 years, many population genetic studies have documented large genetic differences among global ... -
Efficient Shoot Organogenesis Using Leaf Disc and Nodal Explants of Passion Fruit (Passiflora edulis Sims) and Genetic Fidelity Assessment Using Sequence-Related Amplified Polymorphism (SRAP) Markers
(Hindawi International Journal of Agronomy, 2020)Passion fruit (Passiflora edulis (Sims)) is currently ranked third among fruit exports from Kenya and has great potential since the demand for both fresh fruit and processed juice is on a continuous increase. Passion fruit ... -
Varietal differences in physiological and biochemical responses to salinity stress in six finger millet plants
(Physiol Mol Biol Plants, 2020)Finger millet is an important cereal that is grown in semi-arid and arid regions of East-Africa. Salinity stress is a major environmental impediment for the crop growth and production. This study aimed to understand the ... -
Oxacillin Resistant Staphylococcus Aureus Among Hiv Infected and Non-Infected Kenyan Patients
(EAST AFRICAN MEDICAL JOURNAL, 2010)Background: Infections due to methicillin resistant S. aureus (MRSA) present global challenges to clinicians since therapeutic options are limited and suboptimal dosing contributes to heightened mortality and increased ... -
Improved Sample Selection and Preparation Methods for Sampling Plans Used to Facilitate Rapid and Reliable Estimation of Aflatoxin in Chicken Feed
(MDPI, 2021)Aflatoxin B1 (AFB1), a toxic fungal metabolite associated with human and animal diseases, is a natural contaminant encountered in agricultural commodities, food and feed. Heterogeneity of AFB1 makes risk estimation a ... -
Sensitivity of Colletotrichum gloeosporioides Isolates from Diseased Avocado Fruits to Selected Fungicides in Kenya
(Hindawi, 2018)Colletotrichum gloeosporioides is a serious postharvest pathogen of avocado fruits worldwide. Kenya lacks any registered fungicides for the management of the disease. Nevertheless, farmers commonly use commercially available ... -
Variation in Occurrence and Aflatoxigenicity of Aspergillus flavus from Two Climatically Varied Regions in Kenya
(MDPI, 2020)Aflatoxins are carcinogenic chemical metabolites produced by Aspergillus spp. of the section Flavi. In Kenya, Aspergillus flavus is the most prevalent and has been associated with several acute and chronic aflatoxin outbreaks ...
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