Hypoglycemic Effect of Ocimum Lamiifolium in Alloxan Induced Diabetic Mice

Simple item page
dc.contributor.authorArika, W.M.
dc.contributor.authorRachuonyo, H.O.
dc.contributor.authorMuchori, A.N.
dc.contributor.authorLagat, R.C.
dc.contributor.authorMawia, A.M.
dc.contributor.authorWambani, J.R.
dc.contributor.authorWambua, F.K.
dc.contributor.authorNyamai, D.W.
dc.contributor.authorOgola, P.E.
dc.contributor.authorKiboi, N.G.
dc.contributor.authorOuko, R.O.
dc.contributor.authorNjagi, S.M.
dc.contributor.authorMuruthi, C.W.
dc.contributor.authorNgugi, M.P.
dc.contributor.authorNjagi, E.N.M.
dc.date.accessioned2016-02-12T09:11:37Z
dc.date.available2016-02-12T09:11:37Z
dc.date.issued2015
dc.descriptionDOI:10.4172/2167-0412.1000228en_US
dc.description.abstractPlant remedies are the mainstay of treatment in underdeveloped regions owing to the side effects, unavailability and unaffordability of the conventional therapy. Among the traditional plants that have been used as an alternative therapy for diabetes mellitus is Ocimum lamiifolium, however, it has received limited scientific and medical evaluation to assess its efficacy. In this study, the in vivo hypoglycemic activity of aqueous leaf extracts of this plant was determined in male swiss white albino mice. The antidiabetic activity was screened in alloxan induced diabetic mice using oral and intraperitoneal routes. The phytochemical composition was assessed using standard procedures. The extract showed hypoglycemic activity at dose levels of 25, 48.4, 93.5, 180.9, and 350 mg/kg body weight. The extracts contained tannins, sterols, flavonoids, saponins, terpenoids, and alkaloids. The observed hypoglycemic activity could be associated with the phytochemicals present in this plant extract.en_US
dc.identifier.citationMed Aromat Plants 5: 228en_US
dc.identifier.issn2167-0412
dc.identifier.urihttp://ir-library.ku.ac.ke/handle/123456789/14158
dc.language.isoenen_US
dc.publisherOMICS Internationalen_US
dc.subjectDiabetes Mellitusen_US
dc.subjectOcimum lamiifoliumen_US
dc.subjectHypoglycemic activityen_US
dc.subjectAntidiabeticen_US
dc.subjectPhytochemicalen_US
dc.subjectToxicityen_US
dc.titleHypoglycemic Effect of Ocimum Lamiifolium in Alloxan Induced Diabetic Miceen_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Hypoglycemic effect of Ocinum.....pdf
Size:
1.99 MB
Format:
Adobe Portable Document Format
Description:
Full text Article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
RP-Department of Biochemistry and Biotechnology