Bioactive Metabolites from Trichoderma Harzianum and Trichoderma Longibrachiatum

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dc.contributor.authorThoruwa, C. L.
dc.contributor.authorTarus, P. K.
dc.contributor.authorWanyonyi, A. W.
dc.contributor.authorChhabra, S. C.
dc.date.accessioned2014-01-21T12:09:33Z
dc.date.available2014-01-21T12:09:33Z
dc.date.issued2003-03
dc.description.abstractThe tea plant, Camellia sinensis (L.) O. Kuntze is an important crop in the agriculturally based economy of Kenya. Many diseases affect the tea plant but the most prevalent is armillaria root rot caused by the fungus Armillaria mellea. Compounds from the fermentation of Trichoderma species in different media were bioassayed against some selected gram-positive and gram-negative bacteria, fungi including Armillaria mellea, a yeast and a Mucor. Compounds obtained from T. harzianum, and T. longibrachiatum when cultured in various media were investigated individually for in-vitro antifungal and antibacterial activities by agar diffusion technique. Some of the compounds produced definite antifungal and antibacterial activities. 2- Phenylethanol (1) and tyrosol (2) obtained from T. harzianum are reported for the first time from Trichoderma species. The most active metabolite isolated from these strains was 6-n-pentyl-•- pyrone (3), which showed the highest antifungal and antibacterial activity and completely inhibited the growth of Armillaria mellea fungus at a concentration of 200 ppm. Compound 4 (sorbicillin) exhibited moderate activity against the fungal test organisms.en_US
dc.identifier.citationBull. Chem. Soc. Ethiop. 2003, 17(2), 185-190.en_US
dc.identifier.issn1011-3924
dc.identifier.urihttp://ir-library.ku.ac.ke/handle/123456789/8753
dc.language.isoenen_US
dc.publisherChemical Society of Ethiopiaen_US
dc.subjectTrichoderma harzianumen_US
dc.subjectTrichoderma longibrachiatumen_US
dc.subject2-Phenylethanolen_US
dc.subjectTyrosolen_US
dc.subject6-n-Pentyl-•-pyroneen_US
dc.subjectArmillaria Melleaen_US
dc.titleBioactive Metabolites from Trichoderma Harzianum and Trichoderma Longibrachiatumen_US
dc.typeArticleen_US
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