Resolving Intergenotypic Striga Resistance in Sorghum
dc.contributor.author | Mutinda, Sylvia | |
dc.contributor.author | Mobegi, Fredrick M. | |
dc.contributor.author | Hale, Brett | |
dc.contributor.author | Dayou, Olivier | |
dc.contributor.author | Ateka, Elijah | |
dc.contributor.author | Wijeratne, Asela | |
dc.contributor.author | Wicke, Susann | |
dc.contributor.author | Bellis, Emily S. | |
dc.contributor.author | Runo, Steven | |
dc.date.accessioned | 2023-10-26T12:47:29Z | |
dc.date.available | 2023-10-26T12:47:29Z | |
dc.date.issued | 2023-09 | |
dc.description | Article | en_US |
dc.description.abstract | Genetic underpinnings of host–pathogen interactions in the parasitic plant Striga hermonthica, a root parasitic plant that ravages cereals in sub-Saharan Africa, are unclear. We performed a comparative transcriptome study on five genotypes of sorghum exhibiting diverse resistance responses to S. hermonthica using weighted gene co-expression network analysis (WGCNA). We found that S. hermonthica elicits both basal and effector-triggered immunity—like a bona fide pathogen. The resistance response was genotype specific. Some resistance responses followed the salicylic acid-dependent signaling pathway for systemic acquired resistance characterized by cell wall reinforcements, lignification, and callose deposition, while in others the WRKY-dependent signaling pathway was activated, leading to a hypersensitive response. In some genotypes, both modes of resistance were activated, while in others either mode dominated the resistance response. Cell wall-based resistance was common to all sorghum genotypes but strongest in IS2814, while a hypersensitive response was specific to N13, IS9830, and IS41724. WGCNA further allowed for pinpointing of S. hermonthica resistance causative genes in sorghum, including glucan synthase-like 10 gene, a pathogenesis-related thaumatin-like family gene, and a phosphoinositide phosphatase gene. Such candidate genes will form a good basis for subsequent functional validation and possibly future resistance breeding. | en_US |
dc.description.sponsorship | National Academies of Science USAID Arkansas Biosciences Institute African Union Commission German Academic Exchange Service— Deutscher Akademischer Austauschdienst (DAAD) | en_US |
dc.identifier.citation | Mutinda, S., Mobegi, F. M., Hale, B., Dayou, O., Ateka, E., Wijeratne, A., ... & Runo, S. (2023). Resolving intergenotypic Striga resistance in sorghum. Journal of Experimental Botany, 74(17), 5294-5306. | en_US |
dc.identifier.uri | https://doi.org/10.1093/jxb/erad210 | |
dc.identifier.uri | http://ir-library.ku.ac.ke/handle/123456789/27080 | |
dc.language.iso | en | en_US |
dc.publisher | Journal of Experimental Botany | en_US |
dc.subject | Cell wall-based resistance | en_US |
dc.subject | comparative transcriptomics | en_US |
dc.subject | lignin-based resistance | en_US |
dc.subject | parasitic plants | en_US |
dc.subject | pathogenassociated molecular patterns | en_US |
dc.subject | programmed cell death | en_US |
dc.subject | weighted gene co-expression networks | en_US |
dc.title | Resolving Intergenotypic Striga Resistance in Sorghum | en_US |
dc.type | Article | en_US |
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