Absence of Molecular Evidence of Filovirus Circulating In Bats and Rodents in Laikipia North Sub-County, Kenya: A Cross Sectional Study

Simple item page
dc.contributor.authorAmbala, Peris
dc.contributor.authorHussein, Fatima
dc.contributor.authorMutura, Samson
dc.contributor.authorGachara, George
dc.contributor.authorMenza, Nelson
dc.contributor.authorShields, Lindsey Mccrickard
dc.contributor.authorVodzak, Megan
dc.contributor.authorMurray, Susan
dc.contributor.authorValitutto, Marc
dc.contributor.authorZimmerman, Dawn
dc.contributor.authorKamau, Joseph
dc.date.accessioned2023-03-10T06:34:07Z
dc.date.available2023-03-10T06:34:07Z
dc.date.issued2022
dc.descriptionArticleen_US
dc.description.abstractIn the recent decade, pathogenic zoonotic viruses have emerged in different geographical locations almost annually. These changes have led to new complex interactions between humans, animals and the environment, creating unique opportunities for pathogens unique opportunities to pass between hosts. Most emerging pathogens are RNA viruses such as filovirus. Numerous factors such as anthropogenic activities, changes in local ecosystem and climate change have contributed to this spillover. While Kenya has not reported any filovirus outbreaks in humans, a filovirus (i.e Bombali Ebola virus) have been detected in Kenyan bats, which have been implicated as reservoir hosts. The goal of this study was to detect and molecularly characterize known and novel filovirus circulating in bats and rodents in Laikipia North sub-County, Laikipia County, Kenya. In May 2018, a total of 477 samples (blood, oral and rectal swabs) were collected from 159 bats and 159 rodents in Laikipia North sub-County, Kenya. Ribonucleic acid was extracted from all samples and screened using consensus polymerase chain reaction targeting the long-gene of filovirus. All samples were negative. These results suggest that circulation of filovirus was uncommon during the month of May, 2018 in rodents and bats from Laikipia North sub-County. Considering our findings, future sampling should be conducted both longitudinally and with significantly larger sample sizes for a more in depth assessment of the prevalence of filoviruses in bats within the region studied.en_US
dc.description.sponsorshipAnimal species and types of samples collected and map of Kenya (sampling sites).en_US
dc.identifier.citationAmbala, P., Hussein, F., Mutura, S., Gachara, G., Menza, N., Shields, L. M., ... & Kamau, J. Absence of molecular evidence of filovirus circulating in bats and rodents in Laikipia North sub-County, Kenya: a cross sectional study.en_US
dc.identifier.otherPAMJ-OH - 7(34). 21 Apr 2022
dc.identifier.urihttp://ir-library.ku.ac.ke/handle/123456789/24914
dc.language.isoenen_US
dc.publisherhttps://www.one-health.panafrican-med-journal.com/content/article/7/34en_US
dc.subjectEbola virusesen_US
dc.subjectMarburg virusen_US
dc.subjectfilovirusen_US
dc.subjectreservoiren_US
dc.subjectLaikipiaen_US
dc.subjectzoonosisen_US
dc.titleAbsence of Molecular Evidence of Filovirus Circulating In Bats and Rodents in Laikipia North Sub-County, Kenya: A Cross Sectional Studyen_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Absence of Molecular Evidence of Filovirus Circulating In Bats and Rodents in Laikipia North Sub-County, Kenya A Cross Sectional Study.pdf
Size:
990.64 KB
Format:
Adobe Portable Document Format
Description:
Full text Article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
RP-Department of Biochemistry and Biotechnology