Analysis of genetic variability in Anopheles arabiensis and Anopheles gambiae using microsatellite loci

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dc.contributor.authorOrango, S.
dc.contributor.authorField, L. M.
dc.contributor.authorJames, A.
dc.contributor.authorKamau, L.
dc.contributor.authorMukabana, W. R.
dc.contributor.authorHawley, W. A.
dc.contributor.authorLehmann, T.
dc.contributor.authorIrungu, L. W.
dc.contributor.authorCollins, F. H.
dc.date.accessioned2012-10-22T13:37:11Z
dc.date.available2012-10-22T13:37:11Z
dc.date.issued2003-09-10
dc.descriptionhttp//DOI:10.1046/j.1365-2583.1999.820287.xen_US
dc.description.abstractWe analysed genetic variability in Anopheles arabiensis and Anopheles gambiae populations using micro-satellite loci to determine whether the Rift Valley restricts the flow of genes. Deviations from Hardy–Weinberg expectations were significant, and were most likely to be due to the high frequency of null alleles observed. An. arabiensis populations occurring between 40 and 700 km apart across the Eastern arm of the Rift Valley were not differentiated (pair-wise Fst range: 0.0033–0.0265, P > 0.05). Neither were An. gambiae populations from Asembo Bay and Ghana (Fst: 0.0063, P > 0.05) despite a geographical separation of about 5000 km. In contrast, significant differentiation was observed between An. gambiae populations from Asembo Bay and Kilifi (about 700 km apart; FST= 0.1249, P < 0.01), suggesting the presence of a barrier to gene flow.en_US
dc.identifier.citationInsect Molecular Biology Volume 8, Issue 2, pages 287–297, May 1999en_US
dc.identifier.urihttp://ir-library.ku.ac.ke/handle/123456789/5792
dc.language.isoenen_US
dc.publisherWILEYen_US
dc.subjectAnopheles arabiensisen_US
dc.subjectAnopheles gambiaeen_US
dc.subjectgenetic variabilityen_US
dc.subjectmicrosatellite locien_US
dc.subjectpopulation geneticsen_US
dc.titleAnalysis of genetic variability in Anopheles arabiensis and Anopheles gambiae using microsatellite locien_US
dc.typeArticleen_US
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