Prevalence and Patterns of Cervical Cytological Lesions among HIV-Positive Women in Machakos County Hospital Kenya

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dc.contributor.authorMutuku, Onesmus Muia
dc.contributor.authorMathenge, Scholastica Gatwiri
dc.contributor.authorNjoroge, Wachuka Gathigia
dc.contributor.authorKaruga, Titus Kamau
dc.contributor.authorKyama, Cleophas Mutinda
dc.date.accessioned2023-03-28T14:55:32Z
dc.date.available2023-03-28T14:55:32Z
dc.date.issued2021
dc.descriptionArticleen_US
dc.description.abstractBackground: Cervical cancer remains to be a major threat to health among women globally with highest incidences in the developing countries. Studies have showed that HIV-positive women are at higher risk of HPV infection which is the causative agent of cervical cancer. The aim of this study was to determine the prevalence of cervical cytological lesions among HIV infected women in Machakos county hospital Kenya. Study Design: Cross-sectional study. Place and Duration of Study: Machakos County Hospital Comprehensive Care Centre and Machakos Cancer Care and Research Centre, between August 2020 and December 2020. Methodology: A total of 400 women who were HIV-positive and attending the comprehensive care center at the facility were enrolled in this study. Cytological samples obtained using a cytobrush were processed using manual liquid based cytology technique. All smears were stained using the Papanicolaou staining method and examined microscopically for cervical cytological lesions. Chisquare test was performed to evaluate the association between cervical cytological lesions and the demographic variables. Results: A total of 400 participants were enrolled in this study. 15 had unsatisfactory smears and thus excluded from analysis. The prevalence of cervical cytological lesions in this study was 30 out of 385 (7.8%). Of the cervical cytological lesions observed, Atypical Squamous Cells of Undetermined Significance (ASCUS) had the highest number of cases 9 (30%) while Atypical Squamous Cells cannot exclude High grade (ASC-H) had the least number of cases 2 (6.6%). Of all the demographic variables studied, none was found to have any statistical significant association with cervical cytological lesions. Conclusion: The prevalence of cervical cytological lesions among HIV-positive women in this study was 7.8%. There was no statistical significance association between any of the demographic variables studied and cervical cytological lesions.en_US
dc.identifier.citationMuia, M. O. M., Mathenge, S. G., Njoroge, W. G., Karuga, T. K., & Mutinda, K. C. (2021). Prevalence and Patterns of Cervical Cytological Lesions among HIV-Positive Women in Machakos County Hospital Kenya. International Research Journal of Oncology, 4(1), 28-35.en_US
dc.identifier.otherIRJO.66426
dc.identifier.urihttp://ir-library.ku.ac.ke/handle/123456789/25032
dc.language.isoenen_US
dc.publisherInternational Research Journal of Oncologyen_US
dc.subjectPap Smearen_US
dc.subjectCervical Cytological Lesionsen_US
dc.subjectHIV-positive Womenen_US
dc.titlePrevalence and Patterns of Cervical Cytological Lesions among HIV-Positive Women in Machakos County Hospital Kenyaen_US
dc.typeArticleen_US
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