Prevalence and Endoscopic Findings of Helicobacter pylori Infection among Dyspeptic Patients in Kenya

Simple item page
dc.contributor.authorMwangi, Catherine N.
dc.contributor.authorNjoroge, N. Stephen
dc.contributor.authorRajula, Allan
dc.contributor.authorLaving, Ahmed
dc.contributor.authorRose, Kamenwa
dc.contributor.authorSmita, Devani
dc.contributor.authorAndrew, Nyerere
dc.contributor.authorGunturu, Revathi
dc.date.accessioned2025-05-14T12:48:09Z
dc.date.available2025-05-14T12:48:09Z
dc.date.issued2020-12
dc.descriptionArticle
dc.description.abstractBackground: Helicobacter pylori is the most common cause of chronic human infections worldwide with the highest reported prevalence in Africa. It is associated with numerous upper gastrointestinal diseases such as gastritis, peptic ulcers, and gastric cancer. Endoscopic findings in the stomach usually associated with Helicobacter pylori infections include gastritis and gastro- esophageal reflux disease (GERD), however, these findings are suggestive but not diagnostic of Helicobacter pylori infection. Methods: This was a prospective study conducted between January 2018 and February 2019 at the Aga Khan University Hospital where dyspeptic patients scheduled for gastroduodenoscopy were enrolled. These patients were evaluated for Helicobacter pylori infection by rapid urease test, culture and histopathology. Diagnostic findings and patient history collected from medical files were documented and data analyzed. Results: A total of 487 dyspeptic patients undergoing esophagogastroduodenoscopy (EGD) were enrolled in the study and 199 dyspeptic patients were positive for Helicobacter pylori infection. The prevalence was 54.6% in males and 45.4% in females (p = 0.1546. The most common clinical indication and endoscopic findings were heart burn (25.2%) and gastritis (53.7%). Histopathology revealed that 86.1% of the dyspeptic patients had chronic active gastritis (p < 0.005) and 52.8% of them had H. pylori infection. Conclusions: Classical endoscopic findings such as GERD are not always indicative of H. pylori infection as its association with H. pylori infection was not statistically significant in this study.
dc.identifier.citationOgalo, A., & Rugami, J., (2023). Positioning Strategies and Competitive Advantage of Tier One Banks in Mombasa County, Kenya. International Journal of Business Management, Entrepreneurship and Innovation , 5(3), 106-124. https://doi.org/10.35942/axveh492
dc.identifier.issn2165-3380
dc.identifier.otherhttps://doi.org/10.35942/axveh492
dc.identifier.urihttps://ir-library.ku.ac.ke/handle/123456789/30064
dc.language.isoen
dc.publisherScientific Research Publishing
dc.titlePrevalence and Endoscopic Findings of Helicobacter pylori Infection among Dyspeptic Patients in Kenya
dc.typeArticle
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Full Article.pdf
Size:
397.78 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
2.66 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
RP-Department of Medical Microbiology and Parasitology