Antidiabetic Effects of Aqueous Leaf Extracts of Acacia nilotica in Alloxan Induced Diabetic Mice

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dc.contributor.authorMwangi, J. M.
dc.contributor.authorNgugi, M. P.
dc.contributor.authorNjagi, E.N.M.
dc.contributor.authorNjagi, J. M.
dc.contributor.authorAgyirifo, S. D.
dc.contributor.authorGathumbi, K. P.
dc.contributor.authorMuchungi, N. A.
dc.date.accessioned2015-06-18T08:33:17Z
dc.date.available2015-06-18T08:33:17Z
dc.date.issued2015
dc.descriptionResearch Articleen_US
dc.description.abstractDiabetes is increasingly affecting a growing number of patients and seriously reducing their quality of life. Use of conventional drugs in diabetes management is expensive, thus, unaffordable to most patients. Furthermore most of these conventional drugs are associated with undesirable side effects. Incorporation of herbal medicine into conventional healthcare system may significantly improve the overall healthcare system. Evaluation of efficacy and safety by scientific method is necessary to validate herbal medicine utilization, in most cases even where efficacy of the plants has been established the standard dosage required to bring about healing is not clear. This study was designed to designed to evaluate the antidiabetic potential of aqueous leaf extracts of Acacia nilotica in alloxan induced diabetic mice. As the results show, the aqueous leaf extracts of A. nilotica showed antidiabetic activity. The intraperitoneal route of herbal extract administration was found to be more effective than the oral route. Further, qualitative and quantitative phytochemical screening of aqueous leaf extracts of A. nilotica indicated the presence of phenols, alkaloids, flavonoids, tannins and saponins. However, cardiac glycosides and phylobatanins were not detected.en_US
dc.identifier.citationDiabetes Metab 2015, 6:7en_US
dc.identifier.issn1262-3636
dc.identifier.urihttp://ir-library.ku.ac.ke/handle/123456789/12974
dc.language.isoenen_US
dc.publisherElsevier Massonen_US
dc.subjectDiabetes mellitusen_US
dc.subjectAqueous extractsen_US
dc.subjectAntidiabetic activityen_US
dc.subjectPhytochemicalsen_US
dc.titleAntidiabetic Effects of Aqueous Leaf Extracts of Acacia nilotica in Alloxan Induced Diabetic Miceen_US
dc.typeArticleen_US
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