2-Hydroxy-4-Methoxybenzaldehyde: Larvicidal Structure-Activity Studies

Simple item page
dc.contributor.authorNdiege, Isaiah O
dc.contributor.authorLwande, Wilber
dc.contributor.authorAkenga, Teresa O
dc.contributor.authorMahanga, Geoffrey M.
dc.date.accessioned2015-02-10T13:38:40Z
dc.date.available2015-02-10T13:38:40Z
dc.date.issued2005
dc.description.abstract2-Hydroxy-4-methoxybenzaldehyde (1), a compound isolated from Mondia whytei (Hook) Skeels (Asclepiaceae) roots exhibited larvicidal activity (LD5022 mg/mL). A total of 18 other derivatives and closely related congeners revealed varying levels of larvicidal activity. Several closely related congeners, like 2-benzyloxy-4-methoxybenzaldehyde (2), 2-hydroxybenzaldehyde (12), 2-benzyloxybenzaldehyde (3) and benzylphenyl ether (4), showed marked improvement in activity (LD5010, 9, 4.8, 1.2 mg/mL, respectively) against Anopheles gambiae larvae. 2-Benzoyloxy-4-methoxybenzaldehyde (5) exhibited similar activity level (LD50 28 mg/mL) as 1.en_US
dc.identifier.citationJournal Home Vol 19, No 1 (2005)en_US
dc.identifier.urihttp://ir-library.ku.ac.ke/handle/123456789/12198
dc.language.isoenen_US
dc.subject2-Hydroxy-4-methoxybenzaldehyde,en_US
dc.subjectLarvicides,en_US
dc.subjectStructure-activity relationships,en_US
dc.subject2-Hdroxybenzaldehyde,en_US
dc.subject2-Benzyloxybenzaldehyde,en_US
dc.subjectBenzylphenyl ether Anopheles gambiae,en_US
dc.title2-Hydroxy-4-Methoxybenzaldehyde: Larvicidal Structure-Activity Studiesen_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
2-Hydroxy-4-Methoxybenzaldehyde.pdf
Size:
5.14 KB
Format:
Adobe Portable Document Format
Description:
Full Text
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
RP-Department of Chemistry