Long-Distance Transport of Mrna via Parenchyma Cells and Phloem across the Host–Parasite Junction in Cuscuta

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Date
2008
Authors
Rakefet, David-Schwartz
Runo, Steven
Townsley, Brad
Machuka, Jesse
Sinha, Neelima
Journal Title
Journal ISSN
Volume Title
Publisher
New Phytologist
Abstract
It has been shown that the parasitic plant dodder (Cuscuta pentagona) establishes a continuous vascular system through which water and nutrients are drawn. Along with solutes, viruses and proteins, mRNA transcripts are transported from the host to the parasite. The path of the transcripts and their stability in the parasite have yet to be revealed. • To discover the route of mRNA transportation, the in situ reverse transcriptase– polymerase chain reaction (RT-PCR) technique was used to locally amplify host transcript within parasitic tissue. The stability of host mRNA molecules was also checked by monitoring specific transcripts along the growing dodder thread. • Four mRNAs, α and β subunits of PYROPHOSPHATE (PPi)-DEPENDENT PHOSPHOFRUCTOKINASE (LePFP), the small subunit of ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO), and GIBBERELLIC ACID INSENSITIVE (LeGAI), were found to move from host (tomato (Solanum lycopersicum)) to dodder. LePFP mRNA was localized to the dodder parenchyma cells and to the phloem. LePFP transcripts were found in the growing dodder stem up to 30 cm from the tomato–dodder connection. • These results suggest that mRNA molecules are transferred from host to parasite via symplastic connections between parenchyma cells, move towards the phloem, and are stable for a long distance in the parasite. This may allow developmental coordination between the parasite and its host.
Description
article
Keywords
Cuscuta, dodder, in situ RT-PCR, long-distance movement, mRNA trafficking, parasite, phloem
Citation
David‐Schwartz, R., Runo, S., Townsley, B., Machuka, J., & Sinha, N. (2008). Long‐distance transport of mRNA via parenchyma cells and phloem across the host–parasite junction in Cuscuta. New Phytologist, 179(4), 1133-1141.