Antibacterial and Phytochemical Effects of Ethanol Extracts of Syzygium Guineense (Willd.) DC Barks and Mangifera Indica L Seeds
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Date
2023
Authors
Mavanza, Spora Aloyce
Omwenga, George Isanda
Ngugi, Mathew Piero
Journal Title
Journal ISSN
Volume Title
Publisher
JABET
Abstract
Bacterial infectious diseases account for thousands of deaths worldwide. Despite their side
effects, synthetic antibiotics are currently utilized to treat bacterial infections. There has been
an effort to identify alternative medicines of plant origin. Thus, the current study determined
in vitro antibacterial activities of Syzygium guineense barks and seeds of Mangifera indica
ethanol extracts, as well as their phytochemical profile. The tested bacteria included Salmonella
typhi, Staphylococcus aureus, Bacillus subtilis, and Escherichia coli. Plant samples were collected
from Morogoro region, Tanzania and transferred to Kenyatta University for preparation and
extraction. In vitro antibacterial activities were determined by disk diffusion, MIC, and MBC
methods. Selected phytochemicals of ethanol extracts were determined qualitatively. The
highest antibacterial effects were observed in M. indica extract against B. subtilis, S. aureus, E.
coli and S. typhi with zones of inhibition of 20.00 mm, 18.00 mm, 17.67 mm, and 15.67 mm,
respectively. Antibacterial effects observed in S. guineense extract against B. subtilis, S. aureus,
S. typhi and E. coli produced zones of inhibition of 15.00 mm, 14.33 mm, 10.67 mm, and 9.33
mm, respectively. The extracts showed better antibacterial effects against Gram positive
bacteria than Gram negative bacteria. Qualitative phytochemical analysis of the ethanol
extracts revealed alkaloids, quinones, flavonoids, phenolics, saponins, steroids, terpenoids,
tannins, and glycosides. This study indicates that the ethanol extracts of the plants could be
used to develop alternative remedies for treating bacterial infections. The study also suggests
that the plant extracts should be subjected to in vivo studies.
Description
Article
Keywords
Antibacterial, Medicinal plants, Phytochemicals
Citation
Mavanza, S. A., Omwenga, G. I., & Ngugi, M. P. Antibacterial and phytochemical effects of ethanol extracts of Syzygium guineense (Willd.) DC barks and Mangifera indica L seeds.