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dc.contributor.authorMwonjoria, J. K. M.
dc.contributor.authorNgeranwa, J. J. N.
dc.contributor.authorGithinji, C. G.
dc.contributor.authorWanyonyi, A. W.
dc.date.accessioned2019-04-09T08:07:47Z
dc.date.available2019-04-09T08:07:47Z
dc.date.issued2018
dc.identifier.citationJournal of Pharmacognosy and Phytochemistry 2018; 7(6): 1104-1107en_US
dc.identifier.urihttp://ir-library.ku.ac.ke/handle/123456789/19426
dc.descriptionResearch Articleen_US
dc.description.abstractThere are numerous plants whose parts or extracts are used as folklore remedies for disorders such as pain alleviation in Africa. A great majority of these herbal remedies have not been bio- screened for their antinociceptive potential. Euclea divinorum is one such plant that falls within this group where extract from the plant parts is traditionally used in treatment of tooth ache, head ache, chest pain, arthritis, cancers and ulcers. Hence this study was motivated by the desire to scientifically evaluate the antinociceptive activity of the dichloromethane extract of the stem and root bark extract in rats. Pain was induced by injecting 5μl of 5% formalin solution in the sub- planta region of the left hind paw. The biting, lifting, licking and flitching of the affected paw was considered as a sign of pain in rats, and spent in that behavior was quantified from 0-5 minutes (acute pain) and 15-30 minutes inflammatory/neurogenic pain. Keywords: Euclea, divinorum, pain, inflammation, anti-nociceptiveen_US
dc.language.isoenen_US
dc.publisherAkiNik Publicationsen_US
dc.subjectEucleaen_US
dc.subjectDivinorumen_US
dc.subjectPainen_US
dc.subjectInflammationen_US
dc.subjectAnti-nociceptiveen_US
dc.titleAntinociceptive effects of dichloromethane extract of Euclea divinorum Linen_US
dc.typeArticleen_US


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