• Login
    View Item 
    •   Repository Home
    • Research Papers (RP)
    • RP-School of Pure and Applied Sciences
    • RP-Department of Chemistry
    • View Item
    •   Repository Home
    • Research Papers (RP)
    • RP-School of Pure and Applied Sciences
    • RP-Department of Chemistry
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    2-Hydroxy-4-Methoxybenzaldehyde: Larvicidal Structure-Activity Studies

    Thumbnail
    View/Open
    Full Text (5.138Kb)
    Date
    2005
    Author
    Ndiege, Isaiah O
    Lwande, Wilber
    Akenga, Teresa O
    Mahanga, Geoffrey M.
    Metadata
    Show full item record
    Abstract
    2-Hydroxy-4-methoxybenzaldehyde (1), a compound isolated from Mondia whytei (Hook) Skeels (Asclepiaceae) roots exhibited larvicidal activity (LD5022 mg/mL). A total of 18 other derivatives and closely related congeners revealed varying levels of larvicidal activity. Several closely related congeners, like 2-benzyloxy-4-methoxybenzaldehyde (2), 2-hydroxybenzaldehyde (12), 2-benzyloxybenzaldehyde (3) and benzylphenyl ether (4), showed marked improvement in activity (LD5010, 9, 4.8, 1.2 mg/mL, respectively) against Anopheles gambiae larvae. 2-Benzoyloxy-4-methoxybenzaldehyde (5) exhibited similar activity level (LD50 28 mg/mL) as 1.
    URI
    http://ir-library.ku.ac.ke/handle/123456789/12198
    Collections
    • RP-Department of Chemistry [450]

    Designed by Library ICT Team copyright © 2017 
    Contact Us | Send Feedback

     

     

    Browse

    All of RepositoryCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    My Account

    LoginRegister

    Designed by Library ICT Team copyright © 2017 
    Contact Us | Send Feedback