• English
    • français
  • English 
    • English
    • français
  • Login
View Item 
  •   Repository Home
  • Research Papers (RP)
  • RP-School of Pure and Applied Sciences
  • RP-Department of Chemistry
  • View Item
  •   Repository Home
  • Research Papers (RP)
  • RP-School of Pure and Applied Sciences
  • RP-Department of Chemistry
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Microsatellite Typing Reveals Strong Genetic Structure of Schistosoma Mansoni from Localities in Kenya

Thumbnail
View/Open
Abstract (24.58Kb)
Date
2006-11-30
Author
Mburu, D.N.
Agola, L.E.
DeJong, R.J.
Mungai, B.N.
Muluvi, G. M.
Njagi, E.N.M.
Loker, E.S.
Mkoji, G.M.
Metadata
Show full item record
Abstract
Genetic diversity and population structure of seven populations of Schistosoma mansoni sampled in Kenya were assessed using five microsatellite markers. The mean number of alleles per locus, expected heterozygosity in Hardy–Weinberg equilibrium and pairwise FST values ranged from 5.2 to 10.7, 0.5–0.8 and 3.6–27.3%, respectively. These data reveal that S. mansoni populations in Kenyan have relatively high levels of genetic diversity and is significantly differentiated. Our data combined with information on biogeography support the hypothesis that the strong genetic structure in Kenyan schistosomes is as a result of limited gene flow and large population sizes. Resistance to anthelminthics has not been reported among the Kenyan schistosomes, we hypothesize that this is probably due to the very little gene flow among populations, thereby limiting opportunities for the spread of rare alleles that might confer resistance to the drugs.
URI
http://ir-library.ku.ac.ke/handle/123456789/10545
Collections
  • RP-Department of Chemistry [479]

Designed by Library ICT Team copyright © 2017 
Contact Us | Send Feedback

 

 

Browse

All of RepositoryCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

My Account

LoginRegister

Designed by Library ICT Team copyright © 2017 
Contact Us | Send Feedback