RP-Department of Pharmacy & Complementary / Alternative Medicine
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Browsing RP-Department of Pharmacy & Complementary / Alternative Medicine by Author "Gikonyo, N. K."
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Item Repellency property of long chain aliphatic methyl ketones against Anopheles gambiae s.s(African Journals Online, 2008) Innocent, E.; Gikonyo, N. K.; Nkunya, M. H. H.Long chain aliphatic methyl ketone series of C7-C15 were tested for repellency activity against the malaria transmitting mosquito Anopheles gambiae s.s. All methyl ketones produced a dose dependent (P<0.001) repellency response with 2-tridecanone giving comparable protection efficacy to DEET at 10% and 1% concentrations. Aliphatic methyl ketones of C7-C10 had lower activity than those of C11-C15. However, within this range compounds with odd carbon atoms (2-undecanone, 2-tridecanone and 2-pentadecanone) were more effective than compounds with even carbon atoms (2-decanone and 2- dodecanone). Comparable repellency activity of 2-tridecanone to DEET show that, it may save as Anopheles gambiae s.s. mosquito repellent.