Fumigant Toxicity of the Essential Oils of some African Plants against Anopheles Gambiae Sensu Stricto.

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dc.contributor.authorNdiege, I. O.
dc.contributor.authorOmolo, M. O.
dc.contributor.authorOkinyo, D.
dc.contributor.authorLwande, W.
dc.contributor.authorHassanali, Ahmed
dc.date.accessioned2014-01-21T12:43:24Z
dc.date.available2014-01-21T12:43:24Z
dc.date.issued2005-03
dc.description.abstractThe essential oils from 15 species of African plants selected by ethnobotanical considerations and field inspection (odour and presence of insects) were screened for fumigant toxicity to Anopheles gambiae s.s. in the laboratory. Essential oils from 6 species showed varying levels of toxicity, with Conyza newii (Compositae) and Plectranthus marruboides (Labiateae) being the most potent. Fifty compounds representing ∼74% of the essential oil of C. newii were identified by GC-MS and GC-coinjection (for available standards). The major and some of the minor constituents of the two oils were assayed at different doses. Two compounds, from C. newii, perillaldehyde and perillyl alcohol, exhibited higher fumigant toxicity (LD50=1.05×10−4 and 2.52×10−4 mg cm−3, respectively) than the parent oil (2.0×10−3 mg cm−3). GC-MS analysis of the essential oil of P. marruboides gave results similar to that previously reported. Interestingly, none of its components were active, suggesting that the insecticidal activity of the oil results from either some of the minor components or as a blend effect of some of the major constituents.en_US
dc.identifier.citationPhytomedicine. 2005 Mar;12(3):241-6.en_US
dc.identifier.urihttp://ir-library.ku.ac.ke/handle/123456789/8761
dc.language.isoenen_US
dc.publisherPhytomedicineen_US
dc.subjectConyza newiien_US
dc.subjectPlenctranthus marruboidesen_US
dc.subjectCompositaeen_US
dc.subjectLabiateaeen_US
dc.subjectAnopheles gambiaeen_US
dc.subjectFumigant toxicityen_US
dc.subjectEssential oil compositionen_US
dc.subjectPerillaldehydeen_US
dc.subjectPerillyl alcoholen_US
dc.titleFumigant Toxicity of the Essential Oils of some African Plants against Anopheles Gambiae Sensu Stricto.en_US
dc.typeArticleen_US
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