Activity of East African Medicinal Plants against Helicobacter pylori

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dc.contributor.authorFabry, W.
dc.contributor.authorOkemo, P. O.
dc.contributor.authorAnsorg, Rainer
dc.date.accessioned2012-10-24T07:51:19Z
dc.date.available2012-10-24T07:51:19Z
dc.date.issued1996-09
dc.description.abstractThe activity of extracts from the East African medicinal plants Entada abyssinica (stem bark), Terminalia spinosa (young branches), Harrisonia abyssinica (roots), Ximenia caffra (roots), Azadirachta indica (leaves and stem bark) and Spilanthes mauritiana (roots and flowers) were evaluated against 12 strains of Helicobacter pylori. The most active extracts were those derived from T. spinosa with an MIC50 of 125 μg/ml, an MIC90 of 250 μg/ml and an MIC range of 62.5–500 μg/ml. An MIC50 of 250 μg/ml and an MIC90 of > 4,000 μg/ml was reached by H. abyssinica with a range of 125– > 4,000 μg/ml and by X. caffra with a range of 62.5– > 4,000 μg/ml, respectively. It is concluded that these plants contain compounds with antimicrobial activity against H pylori.en_US
dc.identifier.citationChemotherapy. 1996 Sep-Oct;42(5):315-7.en_US
dc.identifier.urihttp://ir-library.ku.ac.ke/handle/123456789/5813
dc.language.isoenen_US
dc.publisherPubmeden_US
dc.subjectEast African plantsen_US
dc.subjectAntibacterial activityen_US
dc.subjectHelicobacter pylorien_US
dc.titleActivity of East African Medicinal Plants against Helicobacter pylorien_US
dc.typeArticleen_US
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