Antibiotic Susceptibility Pattern among Male Patients with Urinary Tract Infection in Special Treatment Centre, Nairobi County, Kenya.
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Date
2019
Authors
Moraa, Dinah
Mathenge, Scholastica
Arodi, Washington
Torome, Tom
Mbuthia, Oliver
Kinyua, Martin
Journal Title
Journal ISSN
Volume Title
Publisher
International Journal of Advanced Multidisciplinary Research and Review (IJAMRR)
Abstract
The occurrence of urinary tract infections in men can be very serious although not very
common. Antibiotic resistance is becoming a global concern and Kenya is no exception.
The aim and objective of the study was to investigate the causative bacteria and antibiotic
susceptibility patterns among male patients with urinary tract infection visiting Special
Treatment Centre, Nairobi County.
Method: A descriptive cross-sectional study design was adopted from January 2018 to
March 2018. Three hundred and eighty four (384) participants were recruited into the study
using systematic sampling technique using structured questioners. Clean morning
midstream urine was then cultured on Cysteine-Lactose-Electrolyte Deficient (CLED) agar
and blood agar medium as per the standard urine culture. Antibiotic sensitivity test was then
done on Mueller-Hinton agar using Kirby-Bauer disk diffusion method according to CLSI
guidelines. Appropriate biochemical tests were done to identify the isolated bacteria.
Results: The highest number of isolates was found to be Escherichia coli isolates (105) and
the least was Pseudomonas auroginosa (12). Ofloxacin, 113(45.2) was found to be most
effective antibiotic (x²=18.2, p=0.01) and the least effective being Augmentin (x²=1.56,
p=0.811). Resistance was found to be high to Nitrofurantoin (65%) and least to Oflocaxin
(13%).
Conclusion: Bacterial cultures and sensitivity should be done on all cases of UTI’s to
determine causative agents so as to guide clinicians in determining the most appropriate
treatment. This will help in addressing cases of emerging multidrug resistance to the
commonly used antibiotics. Follow-up of treated individuals to determine effectiveness of
treatment would also help in addressing cases of failed treatment and prevention of
resistance.
Description
Research Article
Keywords
Antibiotic resistance, Gram positive, Gram negative, Uropathogen
Citation
Moraa, D., Mathenge, S., Washington, A., Tom, T., Mbuthia, O., & Kinyua, M. (2019). Antibiotic Susceptibility Pattern among Male Patients with Urinary Tract Infection in Special Treatment Centre, Nairobi County, Kenya. Int. J. Adv. Multidiscip. Res, 6(2), 36-41.