Semisynthetic Derivatives of Quassin
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Date
1998
Authors
Thoruwa, C. L.
Watt, Robert A.
Toth, Istvan
Phillipson, David J.
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier
Abstract
The natural product quassin has been modified in order to produce compounds with potential antimalarial
action. The modifications include demethylation, reduction of the keto function, esterification with simple organic acids
and- to enhance the uptake through the biological barriers and increase the stability of the compounds - with lipoamino
acids.
Description
Research Article