Bioavailability of Antioxidant Vitamins in Selected Indigeneous Vegetables and their Potential use in Management of HIV/AIDS in Butula, Busia, Kenya
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Date
2024-04
Authors
Nambafu, Rachel Wanjiru
Journal Title
Journal ISSN
Volume Title
Publisher
ACRI
Abstract
The study investigated feeding pattern of PLWHA in Butula division, determined vitamin A, C and E
content and bioavailability in selected indigenous foods for use in the management of HIV and
AIDS. Animal and plants foods accounted for 45.17 %, 21.9 %, 17.48 % and 73 % respectively of
total foods consumed. Fresh blanched vegetables, contained high levels of β-carotene; 4000-
9700µg/100g and α-tocopherol; 3000-7350µg/100g. Solar dried vegetables contained β-carotene
of range 572-854µg/g DW and α-tocopherol of 281-673µg/g DW which is significantly lower
(P<0.05) than fresh vegetables determined by HPLC. L-ascorbic acid content in fresh vegetables
and fruits determined by redox titration ranged from 6 to 65mg/100g. Mean serum retinol, αtocopherol and β-carotene levels were 0.937, 0.144 and 17.787µmol/l respectively determined
using HPLC. CD4+ cell counts in blood determined using flow cytometer were within the normal
range of 500-1500 cells/µl while the CD8+ cell count was in the range of 300-3300 cell/µl of blood.
Hb was less than 12 g/dL and RDW was less than 15.2% indicating anaemia. 88.35% of the
subjects had a CD4/CD8 ratio of less than 1, 9.71% had a CD4/CD8 ratio range of 2-3 and 1.94%
had a ratio greater than 4.77.95% of the subjects had a normal weight, 11.81% were underweight,
8.66% were overweight and 1.57% were obese. Bioavailability in foods estimated using algorithm
indicated a +2.17 change in serum β-carotene and +7.776 changes in serum α-tocopherol levels
indicating that consumption of the foods would result to improving bioavailability of these nutrients
in PLWHA in Butula.
Description
Article
Keywords
Antioxidant vitamins, feeding pattern, PLWHA
Citation
Nambafu, R. W. (2024). Bioavailability of Antioxidant Vitamins in Selected Indigeneous Vegetables and their Potential use in Management of HIV/AIDS in Butula, Busia, Kenya. Archives of Current Research International, 24(4), 221-227.