Larvicidal and IGR activity of extract of Tanzanian plants against malaria vector mosquitoes

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dc.contributor.authorKihampa, Charles
dc.contributor.authorJoseph, Cosam C.
dc.contributor.authorNkunya, Mayunga H.H.
dc.contributor.authorMagesa, S.M.
dc.contributor.authorHassanali, Ahmed
dc.contributor.authorHeydenreich, Matthias
dc.contributor.authorKleinpeter, Erich
dc.date.accessioned2012-10-22T12:21:58Z
dc.date.available2012-10-22T12:21:58Z
dc.date.issued2009-06
dc.description.abstractBackground & objectives: This paper reports the larvicidal activity of seventeen Tanzanian plant species against the malaria vector, Anopheles gambiae s.s. Giles larvae. Some of the plants are used traditionally as sources of insecticidal materials. Methods: The crude extracts from the leaves, stem and root barks of the investigated plants were obtained by solvent extraction and then bio-assayed following WHO protocols showed LC50 values 10 to 400 ppm after 24 h exposure. The structures were determined on interpretation of spectroscopic data. Results: The most active extracts were those from the stem and root barks of Annona squamosa, Uvaria faulknerae, U. kirkii and Uvariodendron pycnophyllum, all of which had LC50 values between 10 and 100 ppm. Long-term exposure beyond 24 h also showed more susceptibility of the larvae to the extracts. Larvae deformities by forming tail-like structures were observed for the methanol extracts of Tessmannia martiniana var pauloi. Interpretation & conclusion: The results suggest that the investigated plant extracts are promising as larvicides against An. gambiae s.s. Giles mosquitoes and could be useful leads in the search for new and biodegradable plant derived larvicide productsen_US
dc.description.sponsorshipGermany Academic Exchange Services (DAAD) through a study grant extended to C.K. through a collaborative research project with the International Centre for Insect Physiology and Ecology (ICIPE) in Nairobi, Kenya, and the Amani Medical Research Centre in Muheza, Tanga, Tanzania.en_US
dc.identifier.citationJ Vector Borne Dis 46, June 2009, pp. 145–152en_US
dc.identifier.urihttp://ir-library.ku.ac.ke/handle/123456789/5785
dc.language.isoenen_US
dc.publisherPubmeden_US
dc.subjectAnopheles gambiae s.s.en_US
dc.subjectbotanical mosquitocidesen_US
dc.subjectIGR activityen_US
dc.subject.ddcAnopheles gambiae s.s.
dc.subject.ddcbotanical mosquitocides
dc.subject.ddcIGR activity
dc.titleLarvicidal and IGR activity of extract of Tanzanian plants against malaria vector mosquitoesen_US
dc.typeArticleen_US
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