Bacterial profile of' bacteremia and septicemia among children under five years visiting Kisii Level 5 hospital in Kisii county, Kenya
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Date
2014-07-28
Authors
Mokua, Evans Chakua
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Abstract
Bacteremia and septicemia in children is an important cause of mortality and morbidity. It is
among the most common health-care associated infections. In recent years, bacteremia and
septicemia infections in children less than five years have been on the increase due to infections
that occur without localized signs or focus of infection, for example, typhoid and non-typhoid
Salmonella infections that are a common cause of bacteremia or those infections whose localized
signs develops later. These infections are treated using first line antibiotics such as Ampicillin,
Chloramphenicol, and Nalixidic acid, Streptomicin, Sulfixozasole, and Tetracycline. However,
multi-drug resistance is an increasing problem. The aim of this study will be to describe the
frequency of occurrence of etiological isolates of bacteremia and septicemia and their
antimicrobial susceptibility patterns at Kisii hospital levelS in Kisii County, Kenya. This crosssectional
study will be carried out at Kisii hospital levelS for children below five years. In this
study, about 150 patients will be enrolled. Blood collected will be cultured, sub cultured and
isolates identified by standard conventional methods such as colonial morphology, Gram stain
method, and confirmed by biochemical tests. The frequency of the various bacterial isolates will
then be determined. The antimicrobial susceptibility of the isolates will be tested using the disk
diffusion method according to Clinical and Laboratory Standard Institute. Data collected will be
analyzed using appropriate biostatical tools and will be used in future management of the
bacteremia and septicemia infections.