Fungistatic and fungicidal activity of east African medicinal plants

dc.contributor.author	Fabry, W.
dc.contributor.author	Okemo, P. O.
dc.contributor.author	Ansorg, R.
dc.date.accessioned	2012-10-25T08:26:28Z
dc.date.available	2012-10-25T08:26:28Z
dc.date.issued	1996-01
dc.description.abstract	Extracts of the traditionally used medicinal plants Entada abyssinica (stem bark), Terminalia spinosa (young branches), Harrisonia abyssinica (roots), Ximenia caffra (roots), Azadirachta indica (stem bark), Zanha africana (stem bark) and Spilanthes mauritiana (roots and flowers) were investigated for fungistatic and fungicidal activity against Candida spp. and Aspergillus spp. by a microtitre serial dilution technique. Entada abyssinica, T. spinosa, X. caffra, A. indica, and Z. africana showed activity against various Candida species. The minimum inhibitory concentrations (MICs) ranged from 0.006 to > 8 mg ml-1 and the minimum fungicidal concentrations (MFCs) from 0.06 to > 8 mg ml-1. Extracts from S. mauritiana (both roots and flowers) exhibited no activity against Candida spp., but against Aspergillus spp., the MIC and MFC values ranged from 0.13 to 0.25 mg ml-1 and from 0.13 to 1 mg ml-1 respectively. It is concluded that the extracts contain compounds with high antifungal potency.	en_US
dc.identifier.citation	Mycoses. 1996 Jan-Feb;39(1-2):67-70.	en_US
dc.identifier.uri	http://ir-library.ku.ac.ke/handle/123456789/5831
dc.language.iso	en	en_US
dc.publisher	Pubmed	en_US
dc.title	Fungistatic and fungicidal activity of east African medicinal plants	en_US
dc.type	Article	en_US

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