Cellular Immune Response and Abomasum worm burden in Goats Vaccinated with HC58cDNA Vaccine against H. contortus Infection

Loading...
Thumbnail Image
Date
2013
Authors
Osuga, Isaac M.
Muleke, C. I.
Yan, Ruofeng
Sun, Yanming
Osuga, I.M.
Shivairo, R.S.
Li, Xiangrui
Journal Title
Journal ISSN
Volume Title
Publisher
www.iiste.org
Abstract
Abstract Vaccination with DNA vaccines derived from adult H. contortus induces significant level of protection against homologous infection in goat. To date however, mechanism of protection is not well understood, especially in goat. In this study, HC58 DNA vaccinated goats were artificially infected with 5, 000 dose of infective H. contortus L 3 (third larval stage), and cellular immune responses and abomasum worm burden examined. The results showed that peripheral CD4+, CD8+ T and B lymphocytes for nematode challenged
Description
Keywords
Citation
Advances in Life Science and Technology, 13, 26-33 2013