Real-Time Operational Research: Case Studies from the Field of Tuberculosis and Lessons Learnt

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dc.contributor.authorHarries, Anthony D.
dc.contributor.authorThekkur, Pruthu
dc.contributor.authorMbithi, Irene
dc.contributor.authorChakaya, Jeremiah Muhwa
dc.contributor.authorTweya, Hannock
dc.contributor.authorTakarinda, Kudakwashe C.
dc.contributor.authorKumar, Ajay M. V.
dc.contributor.authorSatyanarayana, Srinath
dc.contributor.authorBerger, Selma Dar
dc.contributor.authorRusen, I. D.
dc.contributor.authorKhogali, Mohammed
dc.contributor.authorZachariah, Rony
dc.date.accessioned2021-06-16T13:41:53Z
dc.date.available2021-06-16T13:41:53Z
dc.date.issued2021
dc.descriptionArticleen_US
dc.description.abstractReal-time operational research can be defined as research on strategies or interventions to assess if they are feasible, working as planned, scalable and effective. The research involves primary data collection, periodic analysis during the conduct of the study and dissemination of the findings to policy makers for timely action. This paper aims to illustrate the use of real-time operational research and discuss how to make it happen. Four case studies are presented from the field of tuberculosis. These include (i) mis-registration of recurrent tuberculosis in Malawi; (ii) HIV testing and adjunctive cotrimoxazole to reduce mortality in TB patients in Malawi; (iii) screening TB patients for diabetes mellitus in India; and (iv) mitigating the impact of COVID-19 on TB case detection in capital cities in Kenya, Malawi and Zimbabwe. The important ingredients of real-time operational research are sound ethics; relevant research; adherence to international standards of conducting and reporting on research; consideration of comparison groups; timely data collection; dissemination to key stakeholders; capacity building; and funding. Operational research can improve the delivery of established health interventions and ensure the deployment of new interventions as they become available, irrespective of diseases. This is particularly important when public health emergencies, including pandemics, threaten health servicesen_US
dc.identifier.urihttp://ir-library.ku.ac.ke/handle/123456789/22356
dc.language.isoenen_US
dc.publisherMDPIen_US
dc.subjectOperational researchen_US
dc.subjectReal-time operational researchen_US
dc.subjectTuberculosisen_US
dc.subjectCOVID-19en_US
dc.subjectEthicsen_US
dc.subjectResearch capacity buildingen_US
dc.subjectMalawien_US
dc.subjectKenyaen_US
dc.subjectZimbabween_US
dc.subjectIndiaen_US
dc.titleReal-Time Operational Research: Case Studies from the Field of Tuberculosis and Lessons Learnten_US
dc.typeArticleen_US
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