Ultrasonic Synthesis of Silver Nanoparticles Mediated by Prunus africana Plant Extracts and Their Antibacterial Activity

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dc.contributor.authorKithokoi, J. Kilonzo
dc.contributor.authorOchoo, Lawrence
dc.contributor.authorMaingi, John M.
dc.contributor.authorSwaleh, Sauda
dc.contributor.authorNjue, Wilson M.
dc.date.accessioned2023-07-05T08:21:39Z
dc.date.available2023-07-05T08:21:39Z
dc.date.issued2018
dc.descriptionarticleen_US
dc.description.abstractMetal nanoparticles possess unique properties influenced by their size, distribution and morphology. There is increasing interest and demand in metal nanoparticles due to their wide applications in various fields such as medicine, electronics, catalysis, cosmetics and energy. Chemical and physical methods used in synthesis of nanoparticles are costly and unfriendly to the environment due to toxic chemicals involved. Green synthesis is rapid; cost friendly and involve non-toxic chemicals. Plants provide unique platform for green synthesis of metal nanoparticles over other green synthetic methods as they stabilize and cap the nanoparticles with biomolecules. In this study, Prunus africana stem bark extract was used to synthesize silver nanoparticles (AgNPs) on ultrasonic bath. The formation of AgNPs was monitored visually through colour change and by UV-Vis spectroscopy. The Energy Dispersive X-ray (EDX) analysis showed that the AgNPs were pure silver. HRTEM analysis indicated evenly distributed, monodispersed and spherical AgNPs with the average size of 23±3.06nm. FTIR analysis showed the presence of hydroxyl and -C=C- groups an indication of presence of phenolic compounds. The antibacterial activity of the synthesized AgNPs was tested against E. coli and S. aureus and were found to be toxic against these pathogens with maximum zones of inhibition of 14.21±0.208mm and 16.03±0.204mm respectively. MIC for both E. coli and S. aureus was 0.25mM. No previous reports on synthesis of silver nanoparticles using P. africana. The study contributes towards application of P. africana extracts in generation of novel silver nanoparticles for development of drugs useful in fight against bacterial infectionsen_US
dc.identifier.citationKithokoi, J.  Kilonzo. “Ultrasonic Synthesis of Silver Nanoparticles Mediated by Prunus Africana Plant Extracts and Their Antibacterial Activity.” International Journal of Nano and Material Sciences, 5 Dec. 2018, www.ModernScientificPress.com/Journals/ijnanos.aspx.en_US
dc.identifier.issn2166-0182
dc.identifier.urihttp://ir-library.ku.ac.ke/handle/123456789/26077
dc.language.isoenen_US
dc.publisherModern Scientific Pressen_US
dc.subjectAgNPsen_US
dc.subjectP. africanaen_US
dc.subjectHRTEMen_US
dc.subjectEDXen_US
dc.subjectantibacterial activityen_US
dc.titleUltrasonic Synthesis of Silver Nanoparticles Mediated by Prunus africana Plant Extracts and Their Antibacterial Activityen_US
dc.typeArticleen_US
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