Repellency and Composition of Essential Oils of Selected Ethnobotanical Plants Used in Western Kenya against Bites of Anopheles gambiae Sensu Stricto

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dc.contributor.authorYwaya, David O.
dc.contributor.authorBirkett, Michael A.
dc.contributor.authorPickett, John A.
dc.contributor.authorOchola, John B.
dc.contributor.authorLwande, Wilber
dc.contributor.authorWachira, Benson M.
dc.contributor.authorHassanali, Ahmed
dc.contributor.authorNg’ang’a, Margaret M.
dc.date.accessioned2020-09-16T09:57:13Z
dc.date.available2020-09-16T09:57:13Z
dc.date.issued2020
dc.descriptionA research article published in Journal of Essential Oil Bearing Plantsen_US
dc.description.abstractThe essential oils of Ocimum gratissimum Linn, Hyptis suaveolens (L) Poit and Vitex keniensis, which are used traditionally in Western Kenya for personal and space protection against mosquito bites, were screened for repellence against Anopheles gambiae Sensu Stricto. Essential oils were extracted from their leaves by hydrodistillation, characterised by gas chromatography linked with mass spectrophotometer and electroantennogram detectors. The repellency of the oils and their selected blends was studied by the reduction in probing and feeding on the human arm. The oils showed promising repellency for Anopheles gambiae, O. gratissimum (RD50 = 2.77 × 10-5 mg cm-2, 95 % CI), Vitex keniensis (RD50 = 5.68 × 10-5 mg cm-2) and Hyptis suaveolens (6.27× 10-5 mg cm-2) as compared to that of DEET (control) RD50 = 1.25×10-5 mg cm-2). The bioactive constituents of each oil were identified by Gas chromatography-linked with Mass spectrometry and Electroantennography. Some compounds were confirmed by co-injections of the oil with available authentic standards. The results provide a scientific rationale for the traditional use of these plants in repelling disease vectors and other biting insects, and lay down some useful groundwork for downstream development of more effective products for personal and space protection.en_US
dc.identifier.citationDavid O. Ywaya , Michael A. Birkett , John A. Pickett , John B. Ochola , Lwande Wilber , Benson M. Wachira , Ahmed Hassanali & Margaret M. Ng’ang’a (2020) Repellency and Composition of Essential Oils of Selected Ethnobotanical Plants Used in Western Kenya against Bites of Anopheles￿gambiae Sensu Stricto, Journal of Essential Oil Bearing Plants, 23:3, 432-441, DOI: 10.1080/0972060X.2020.1780954en_US
dc.identifier.issn0976-5026
dc.identifier.otherDOI: 10.1080/0972060X.2020.1780954
dc.identifier.urihttps://doi.org/10.1080/0972060X.2020.1780954
dc.identifier.urihttp://ir-library.ku.ac.ke/handle/123456789/20372
dc.language.isoenen_US
dc.publisherTaylor & Francis Groupen_US
dc.subjectAnopheles gambiaeen_US
dc.subjectethnobotanicalsen_US
dc.subjectOcimum gratissimumen_US
dc.subjectHyptis suaveolensen_US
dc.subjectVitex keniensisen_US
dc.subjectrepellencyen_US
dc.subjectessential oilsen_US
dc.subjectbioactive constituents.en_US
dc.titleRepellency and Composition of Essential Oils of Selected Ethnobotanical Plants Used in Western Kenya against Bites of Anopheles gambiae Sensu Strictoen_US
dc.typeArticleen_US
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