Detection and Management of Adverse Drug Reactions Related to Antiretroviral Drugs among HIV/AIDS Patients in Kiambu Sub-County, Kenya

Simple item page
dc.contributor.authorNderitu, F. W.
dc.contributor.authorGikonyo, N. K.
dc.contributor.authorSinei, K. A.
dc.date.accessioned2017-11-27T09:45:10Z
dc.date.available2017-11-27T09:45:10Z
dc.date.issued2013
dc.descriptionResearch Articleen_US
dc.description.abstractThe objective of this study was to establish the detection, prevalence and management of various adverse drug reactions associated with antiretroviral drugs occurring in patients attending Comprehensive Care Centre (CCC) of Kiambu District Hospital. The study was a cross sectional survey where the patients included were those attending the CCC on a monthly basis. The results revealed that 65.2% of the patients had experienced symptoms suggestive of adverse drug reactions (ADRs). Of these, 67.2% did not associate the symptoms to the medicines they were taking but rather to the AIDS syndrome. The most prominent reaction was peripheral neuropathy at 0.395 (0.344-0.447 at 95% confidence interval) while the least common was hepatotoxicity. Whereas 71.5% could tell the frequency of the daily dosage, 92.1% did not know the names of the medicines they were taking but could describe them by shape and colour. There was a significant association between occurrence and reporting of ADRs and age (P<0.001), weight (P=0.001), marital status (P=0.016), occupation (P<0.001), religious participation (P<0.001) and education level (P<0.001). Although the health care providers displayed adequate knowledge in management of these reactions, they complained of inadequacy of the current reporting tool (MOH 257) in capturing ADRs. The patients were ill equipped in recognising the ADRs.en_US
dc.identifier.citationEast and Central African Journal of Pharmaceutical Sciences Vol. 16 (2013) 3-12en_US
dc.identifier.urihttp://ir-library.ku.ac.ke/handle/123456789/17864
dc.language.isoenen_US
dc.publisherAfrican Journals Onlineen_US
dc.subjectAdverse drug reactionsen_US
dc.subjectOccurrenceen_US
dc.subjectDetectionen_US
dc.subjectManagementen_US
dc.titleDetection and Management of Adverse Drug Reactions Related to Antiretroviral Drugs among HIV/AIDS Patients in Kiambu Sub-County, Kenyaen_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Detection and management of adverse.....pdf
Size:
354.48 KB
Format:
Adobe Portable Document Format
Description:
Full Text Article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
RP-Department of Public Health