Laboratory Evaluation of some Eastern African Meliaceae as Sources of Larvicidal Botanicals for Anopheles Gambiae
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Date
2004
Authors
Hassanali, Ahmed
Ndung’u, Mary
Torto, B.
Knols, B. G .J.
Journal Title
Journal ISSN
Volume Title
Publisher
ICIPE
Abstract
Root bark extracts of five Meliaceae species (
Turraea abyssinica
Hochst.,
Turraea
wakefeldii
Oliv.,
Turraea mombassana
Hiern ex C.DC.,
Trichilia roka
(Forsk) Chiov. and
Melia
volkensii
Guerke.) and different fractions thereof (following chloroform extraction and
column chromatographic separation) were compared for their immediate toxicity and
long-term effects on
Anopheles gambiae
Giles
sensu stricto
(Diptera: Culicidae). Larvicidal
effects of the extracts appeared to be largely associated with limonoids of medium polarity
with
M. volkensii
and
T. mombassana
extracts being more potent than those of the other
Meliaceae. Long-term (6 – 8 days post-exposure) observations at lower doses showed that
100% cumulative mortality can be achieved with some extracts (particularly those of
T. mombassana
and
M. volkensii
) with interesting growth-inhibition effects. Follow-up
studies that are needed and practical implications of the results in terms of development of
larval control strategies for African malaria vectors are discussed
Description
DOI: 10.1079/IJT200435
Keywords
Citation
nternational Journal of Tropical Insect Science Vol. 24, No. 4, pp. 311–318, 2004