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dc.contributor.authorGicheru, M. M.
dc.contributor.authorMutiso, J. M.
dc.contributor.authorMacharia, J. C.
dc.date.accessioned2014-01-14T15:26:26Z
dc.date.available2014-01-14T15:26:26Z
dc.date.issued2010
dc.identifier.urihttp://ir-library.ku.ac.ke/handle/123456789/8549
dc.descriptiondoi: 10.1016/S1674-8301(10)60004-8.en_US
dc.description.abstractOver the last decade, there has been a flurry of research on adjuvants for vaccines, and several novel adjuvants are now licensed products or in late stage clinical development. The success of adjuvants in enhancing the immune response to antigens has led many researchers to re-focus their vaccine development programs. Although several vaccine candidates have been tested against leishmaniasis, there is yet no effective vaccine against this parasitic disease. Recent research has documented that efforts to develop effective Leishmania vaccine have been limited due to lack of an appropriate adjuvant. In view of this, this review paper outlines some of the adjuvants that have been used in Leishmania vaccine candidates and cites a few of the responses obtained from these studies. The aim of the present review is to consolidate these findings to facilitate the application of these adjuvants in general and experimental vaccinology.en_US
dc.language.isoenen_US
dc.publisherPubMeden_US
dc.subjectAdjuvantsen_US
dc.subjectLeishmania vaccinesen_US
dc.subjectImmune responsesen_US
dc.subjectLeishmaniasisen_US
dc.titleA Review of Adjuvants for Leishmania Vaccine Candidates.en_US
dc.typeArticleen_US


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