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Pentacyclic triterpenoids from Embelia schimperi.

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Date
2003
Author
Machocho, Alex K.
Kiprono, P.C.
Grinberg, S.
Bittner, S.
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Abstract
Five oleanane-type pentacyclic triterpenoids were isolated by chromatographic separation of a chloroform extract of the stem bark of Embelia schimperi. Three of these compounds have a methyleneoxy bridge. Two compounds, embelinone and schimperinone, are reported here for the first time from a natural source (they have been synthesized previously during chemical transformations). Their structures were determined by spectroscopic techniques, among which 2-D NMR was useful for complete characterization. Three of the triterpenoids exhibited mild antibacterial properties against the gram-positive bacterial strain Rhodococcus sp.
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http://ir-library.ku.ac.ke/handle/123456789/7453
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  • RP-Department of Chemistry [479]

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