Non-epec typable escherichia coli serotypes causing urinary tract infections at a University community clinic, Nairobi, Kenya
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Date
2010
Authors
Okemo, P. O.
Kimando, J. M.
Journal Title
Journal ISSN
Volume Title
Publisher
International Journal of Pharma and Bio Sciences
Abstract
Escherichia coli is the predominant cause of urinary tract infections, and is gaining prominence in medical
practice due to increasing resistance to widely used antimicrobials including some specified in the world
Health Organization’s Model List of Essential Drugs. A cross-sectional analytical research design was
conducted to determine the serotypes and antimicrobial resistance phenotypes of Escherichia coli isolated
from patients with symptomatic urinary infections. Results obtained show that among the typable
enteropathogenic Escherichia coli, serotype 4 was predominant. Over 85 percent of the isolates were sensitive
to ceftazidime, ciprofloxacine, gentamicin, norfloxacine and nitrofurantoin. More than 82 percent of the
isolates were resistant to cotrimoxazole and ampicillin, 58.69 percent resistant to augmentin and 31.52 percent
resistant to nalidixic acid. The drugs ampicillin and cotrimoxazole exhibited minimum inhibitory
concentration >2000μg/ml. Most strains were multi drug resistant, and 93 percent of the isolates carried
plasmids of molecular weight range 1.8 to 98 MDa.
Description
Available online at http://www.ijpbs.net/46.pdf
Keywords
Escherichia coli, serotypes, resistance phenotypes, plasmids