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dc.contributor.authorNyamache, A. K.
dc.contributor.authorMuigai, A. W.
dc.contributor.authorKhamadi, S. A.
dc.date.accessioned2012-10-15T13:01:35Z
dc.date.available2012-10-15T13:01:35Z
dc.date.issued2012-10
dc.identifier.citationAIDS Res Hum Retroviruses. 2012 Oct 4.en_US
dc.identifier.urihttp://ir-library.ku.ac.ke/handle/123456789/5620
dc.description.abstractAs the AIDS pandemic progresses, an increasingly broad range of genetic diversity continues to be reported within the main (M) group of HIV-1 viruses with viral subtype predominating in specific geographic areas. To determine the genetic diversity of HIV-1 subtypes among Kenyan individuals, the env-C2-V3 gene was successfully sequenced in samples from 176 patients. Analysis of the sequences showed that a majority of them belonged to subtype A1: 73.9% (130/176), followed by C: 10.8% (19/176), D: 10.2% (18/176), and 0.6% (1/176) for G and A2 as pure subtypes while the rest were recombinants of A1/U: 2.3% (4/176) and 0.6% (1/176) each for D/U, A/C/U, and AC. Similar to previous studies conducted in other parts of Kenya, HIV-1 subtype A1 still remains the most predominant subtype while subtype C continues to show an increasing prevalence. Continued surveillance of circulating subtypes of HIV-1 in Kenya is important in determining the evolution of the HIV/AIDS epidemic in Kenya.en_US
dc.language.isoenen_US
dc.publisherPubmeden_US
dc.subjectAIDSen_US
dc.subjectHIV-1 Virusen_US
dc.titleCirculating Trends of Non-B HIV Type 1 Subtypes Among Kenyan Individualsen_US
dc.typeArticleen_US


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