Antibacterial activity of green synthesized silver nanoparticles using Citrullus lanatus fruit rind extract
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Date
2020
Authors
Ndikau, Michael
Naumih, Noah
Andala, Dickson
Masika, Eric
Journal Title
Journal ISSN
Volume Title
Publisher
Kenya Chemical Society
Abstract
The increased resistance of microbes to current antibiotics calls for development of new effective antimicrobial agents. Metal
nanoparticles such as silver nanoparticles have continued to attract increased research interest in the recent past because of their wide
range of applications such as in the areas of chemical sensing, nanomedicine and electronics. In this work, spherical AgNPs (17.96 ±
0.16 nm in diameter) synthesized via a green method using Citrullus lanatus (water melon) fruit rind extract were evaluated for
antimicrobial activity against clinical isolates of Escherichia coli (E.coli) and Salmonella typhi (S.typhi) bacteria using the discdiffusion method. The Minimum Inhibition Concentration (MIC) value of the nanoparticles was found to be 45.00 ± 0.01 g/ml for
S.typhi and 38.50 ± 0.00 g/ml for E.coli while the Minimum Bactericidal Concentration (MBC) value was found to be 60.00 ± 0.05
g/ml for S.typhi and 50.00 ± 0.00 g/ml for E.coli. This study demonstrated that these two bacterial strains were susceptible to the
green synthesized AgNPs.
Description
A research article published in the Journal of the Kenya Chemical Society
Keywords
Green synthesis, Antimicrobial activity, Silver nanoparticles, Citrullus lanatus
Citation
Ndikau, M., Noah, N., Andala, D., & Masika, E. (2020). Antibacterial activity of green synthesized silver nanoparticles using Citrullus lanatusfruit rind extract.