RP-Department of Pre-clinical Sciences

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Browsing RP-Department of Pre-clinical Sciences by Subject "Hypertension"

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    Patient related barriers to adequate blood pressure control among adult hypertensive patients seen at Kiambu County Hospital, Kenya
    (East and Central Africa Medical Journal, 2020) Kibore Mogondo, Antony; Moturi, George; Thigiti, Joseph
    Introduction: Hypertension is a key precursor to cardiovascular and renal disease globally. According to WHO, Prevalence of hypertension was about 40 % globally in 2015 and 45% in Sub Saharan Africa in 2015. Despite much emphasis on treatment of the syndrome, the related blood pressure control remains poor or inadequate. Objective: The study sought to establish the patient related barriers to adequate blood pressure control among adult hypertensive patients in Kiambu Count Hospital in Kenya. Methods: A cross -sectional descriptive study method approach was used to examine sample of 330 patients selected through consecutive sampling technique in the medical outpatient chronic disease clinic. Multivariate logistic regression analysis was used to determine variables associated with inadequate or poorly controlled hypertension among adult patients. Results: Most of the patients were females (71.5%). However, the presence of inadequate blood pressure control was significantly higher among males (P-value= 0.009). Regularly taking of hypertension drugs for the last 6 months was significantly associated with adequate blood pressure control (p-value=0.033). The other barriers including single status, inadequate knowledge, employment and time duration since diagnosis of hypertension did not significantly affect blood pressure control status. Discussion: Males were 54% more likely to have inadequate blood pressure control compared to females (AOR=0.543; 95%CI=0.323-0.914). Patients with low adherence to treatment were 11% more likely to have inadequate blood pressure control than those with high adherence rate (AOR=1.093; 95%CI=0.224-5.332) though the association was not significant (p-value=0.912). Conclusion: Male gender was a major barrier to adequate blood pressure control. Patients who well adhered to treatment scheme for a duration of six months preceding the study had their blood pressure better controlled than those who did not. Male hypertensive patients need to be followed up to ensure they adhere to drug treatment in order to reduce the rates of inadequate blood pressure control and other related complications.
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    Uptake of Chronic Kidney Disease Preventive Measures among Diabetic and Hypertensive Patients at the Nyeri County Referral Hospital, Kenya
    (IJRESM, 2023) Wakhungu, Liner; Githemo, Grace; Wala, Jonathan
    The rise in chronic kidney disease (CKD) prevalence worldwide is alarming. It is associated with substantial mortality and morbidity, thus demanding special consideration as one of the increasing public health concerns. Hypertension and diabetes pose the highest risk for CKD development. The study objective was to establish the factors that influence CKD preventive practices among diabetes and hypertension patients at Nyeri County Referral Hospital (NCRH). Data was obtained from 190 participants by the use of a questionnaire. Data was analyzed using SPSS and presented using descriptive statistics. Chi-square was used to test for association among variables while multiple regression analysis was used to test for the predictors of CKD prevention uptake. The findings revealed that 84.2% of the participants had good CKD prevention uptake. Gender χ2 (1) = 6.243, p= .012 age χ2 (4) = 13.146, p= .011, and income χ2 (4) = 25.467, p <0.001 were significantly associated with CKD preventive practice uptake. Health care provider communicating to DM/HTN patients in a language they could understand χ2 (2) = 18.102, p<0.001, accessing all the laboratory services within the hospital χ2 (2) = 8.469, p=.014 and being able to obtain the prescribed drugs from the hospital pharmacy χ2 (2) = 6.361, p=.043 were significantly associated with CKD prevention uptake. The predictors for CKD prevention uptake included gender, income, age, and being well informed about the disease condition. In conclusion 84.2% of the participants had good CKD prevention uptake and this was influenced by factors stated above. The study recommends that health care providers in Nyeri County Referral Hospital should provide CKD prevention health education program especially to the at-risk population. The health care services should also be made available, accessible and affordable to diabetic and hypertensive patients.