Browsing by Author "Maina, Ngotho"

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    Recent Trends of Vibrio cholerae: Global and Regional Incidences
    (2025) Siamalube,Beenzu; Ehinmitan,Emmanuel; Runo,Steven; Onguso,Justus; Maina, Ngotho
    Cholera is still with us! The foodborne/waterborne dis ease caused by the bacterium Vibrio cholerae continues to pose a significant threat to the safety of public health glob ally (Mohammed et al., 2024). Despite various medical inter ventions such as the use of oral cholera vaccines (OCVs) (Zeitoun et al., 2024), hundreds of thousands of lives are lost annually worldwide to this virulent disease. Cholera mostly affects vulnerable populations in regions with inadequate access to clean water and sanitation (Bose et al., 2024). Recent outbreaks in parts of Asia (Nasr et al., 2024), Africa (Taty et al., 2024), and the Caribbean underscore the ongoing risk and the urgent need for comprehensive strategies to control its spread (Siamalube and Ehinmitan, 2024). This commentary aims to unravel the challenges caused by V. cholerae by exploring the global cholera inci dences and the multifaceted approaches required to combat this persistent pathogen
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    The Persistent Challenge of Cholera in Africa: A Complex Interplay of Factors
    (RPHB, 2024-12) Siamalube, Beenzu; Ehinmitan, Emmanuel; Runo, Steven; Onguso, Justus; Maina, Ngotho
    Cholera remains a formidable public health challenge across Africa, disproportionately impacting marginalized and vulnerable populations [1]. The disease's persistence underscores its multifaceted nature, rooted in more than just the biological characteristics of Vibrio cholerae. Instead, it reflects a complex interplay of environmental, social, economic, and systemic factors, each compounding the difficulty of effective prevention and control [1,2]. Africa continues to bear the highest burden of cholera globally, with recurring outbreaks that cause significant morbidity and mortality, often overwhelming already fragile healthcare systems [3]. The disease frequently strikes regions plagued by inadequate access to clean water, sanitation, and hygiene (WASH) infrastructure [3,4]. These deficiencies create fertile ground for the bacterium's proliferation, particularly in densely populated urban slums and rural areas with limited public health outreach. Climate change further exacerbates the problem, with extreme weather events such as floods and droughts creating conditions conducive to cholera outbreaks [5].