PT-school of Pure and Applied Sciences

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Browsing PT-school of Pure and Applied Sciences by Author "Cheche, Peris Wangari"

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    Prevalence of catheter associated urinary tract infections among patients hospitalised at the Nyeri county referral hospital
    (Kenyatta University, 2014-09-26) Cheche, Peris Wangari
    Urinary tract infection, a type of health care infection is the most common nosocomial infection accounting for up to 40% of infections reported by acute hospitals and approximately 18% to 25% of all nosocomial bacteremias. Up to 80% of urinary tract infections are associated with the presence of an indwelling catheter. Catheter associated urinary tract infections can result in increased morbidity, mortality, hospital cost, and length of stay. The infections are caused by Gram negative bacteria, Gram positive bacteria and Candida species. The infections are treated by common antimicrobial agents which include: Cotrimoxazole, Amoxylin, Gentamycin, Augmentin, Ceftriaxone, Erythromycin, Nalixidic acid and nitrofurantoin. However multiple drug resistance has been a problem in controlling the infections. The aim of this study will be to isolate and identify microorganisms causing the infections, their antimicrobial resistance levels and the influence of the catheters duration, age and gender of the patient on the infections at the Nyeri County Referral Hospital. In this study 175 patients will be enrolled. About 10 ml of urine will be collected and cultured using standard conventional methods. The isolated microorganisms will be identified using their colonial morphology, Gram stain and confirmed by biochemical tests. The antimicrobial susceptibility of the isolates will be tested using the disk diffusion method according to the Clinical and Laboratory standard institute (CLSI). Data collected will be analyzed using statistical package for social sciences (SPSS) 20.0 and would be used in future by clinicians in the management of patients with catheters as well as in making decisions on antibiotic prescriptions .