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Characterization of occult hepatitis B virus infection among HIV positive patients in Cameroon 

Gachara, George; Magoro, Tshifhiwa; Mavhandu, Lufuno; Lum, Emmaculate; Kimbi, Helen K.; Ndip, Roland N.; Bessong, Pascal O. (BioMed Central, 2017)
Purpose: Occult hepatitis B infection (OBI) among HIV positive patients varies widely in different geographic regions. We undertook a study to determine the prevalence of occult hepatitis B infection among HIV infected ...
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Polymorphic Variability in the Interleukin (IL)-1Beta Promoter Conditions Susceptibility to Severe Malarial Anemia and Functional Changes in IL-1Beta Production 

Otieno, Micheal Frederick; Ouma, C.; Davenport, G. C.; Awandare, G. A.; Keller, C. C.; Were, T.; Vulule, J. M.; Martinson, J.; Ong'echa, J. M.; Ferrell, R. E.; Perkins, D. J. (PubMed, 2008-10)
Interleukin (IL)-1beta is a cytokine released as part of the innate immune response to Plasmodium falciparum. Because the role played by IL-1beta polymorphic variability in conditioning the immunopathogenesis of severe ...
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Non-Hepatic Adverse Effects of Antiretroviral Therapy for HIV Treatment and Care 

Wambani, J.R.; Ogola, P.E.; Makori, A.W.; Rachuonyo, H.O.; Kiboi, N.G. (Adis, Springer Healthcare, 2016)
High-level viral replication occurs when HIV enters the body. Due to frequent mutations, the virus becomes resistant in the body and persists in memory T cells making it incurable. Lifelong therapy is then required ...
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Characterization of occult hepatitis B in highrisk populations in Kenya 

Kiptoon, Beatrice Jepkemei; Missiani, Ochwoto; Swidinsky, Ken; Day, Jacqueline; Gebrebrhan, Henok; McKinnon, Lyle R.; Andonov, Anton; Oyugi, Julius; Kimani, Joshua; Gachara, George; Songok, Elijah Maritim; Osiowy, Carla (PLOS ONE, 2020)
Occult hepatitis B infection (OBI) is defined as the presence of hepatitis B virus (HBV) DNA in the liver or serum in the absence of detectable HBV surface antigen (HBsAg). OBI poses a risk for the development of cirrhosis ...
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Oil Contents and Aflatoxin Levels in Peanuts Varieties Produced in Busia and Kisii Central Districts, Kenya 

Menza, Nelson C.; Muturi, Margaret W.; Kamau, Lucy M. (OMICS International, 2016)
Busia and Kisii Central districts have repeatedly reported high levels of aflatoxins in foods. The objectives of the study were to determine oil contents and the relationship between oil contents and the levels of total ...
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Rectal Gonorrhoea and Chlamydia among Men Who Have Sex with Men in Coastal Kenya 

Ngetsa, Caroline J.; Heymann, Marc W.; Thiong'o, Alex; Wahome, Elizabeth; Mwambi, John; Karani, Clara; Menza, Nelson C.; Mwashigadi, Grace; Muturi, Margaret W.; Graham, Susan M.; Mugo, Peter M.; Sanders, Eduard J. (Wellcome Open Research, 2020)
Background: Men who have sex with men (MSM) have a higher prevalence of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infections compared to the rest of the population, often remaining undiagnosed. In Kenya, ...
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Potency status of oral polio virus vaccine among retrieved field samples in Kenya 

Gachara, George; Hassan, J. A.; Mbugua, F.; Muchiri, J.; Symekhah, S.; Nakitari, G.; Borus, P.; Kamau, T.; Kombich, J. (Elsevier, 2014-04)
Background: In 1988 the World Health Organization (WHO) proposed mass immunization campaigns with the trivalent oral polio vaccine (TOPV) among children less than 5 years of age. The Vaccine Vial Monitor (VVM) is a small ...
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Prevalence of Bacterial Vaginosis among HIV-Positive Women in Machakos County Hospital, Kenya 

Mutuku, Onesmus Muia; Scholastica, Gatwiri Mathenge; Wachuka, Gathigia Njoroge; Karuga, Titus Kamau; Kyama, Cleophas Mutinda (Asian Research Journal of Gynaecology and Obstetrics, 2021)
Background: Bacterial vaginosis (BV) is a common infection in women during their reproductive age. However, the burden of BV among HIV-positive women in Kenya is not clear. This study aimed to determine the ...
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Combining Evidence of Natural Selection with Association Analysis Increases Power to Tetect Malaria-Resistance Variants. 

Otieno, Micheal Frederick; Ayodo, G.; Price, A. L.; Keinan, A.; Ajwang, A.; Orago, A. S.; Patterson, N.; Reich, D. (PubMed, 2007)
Statistical power to detect disease variants can be increased by weighting candidates by their evidence of natural selection. To demonstrate that this theoretical idea works in practice, we performed an association study ...
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Evolutionary Pattern of the Hemagglutinin Gene of Influenza B Viruses Isolated in Kenya 2005-2009 

Gachara, George; Bulimo, W.; Magana, J.; Simwa, J.; Symekher, S. (African Journal of Health Sciences, 2011-06-17)
Background: In humans, the inability to provide lasting protection against influenza B virus infection is due, in part, to the rapid evolution of the viral surface glycoprotein, haemagglutinin (HA), which leads to a change ...
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AuthorGachara, George (8)Bulimo, W. (3)Magana, J. (3)Muturi, Margaret W. (3)Otieno, Micheal Frederick (3)Fardolo, Ezekiel Kanue (2)Gachara, George (2)Mathenge, Scholastica (2)Mathenge, Scholastica G. (2)Menza, Nelson C. (2)... View MoreSubjectKenya (5)Peanuts (3)Aflatoxins (2)Blood Donors (2)Klebsiella pneumoniae (2)Prevalence (2)2019-nCoV Misinformation (1)Acute Respiratory Infection (ARI) (1)Adolescents (1)Adverse effects (1)... View MoreDate Issued2020 - 2022 (10)2010 - 2019 (20)2000 - 2009 (3)1991 - 1999 (1)

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