Parcourir RP-Department of Medical Physiology par date de publication
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Over-diagnosis and co-morbidity of severe malaria in African children: a guide for clinicians.
(The American Journal of Tropical Medicine and Hygiene, 2007-12)Severe malaria is clinically similar to other severe febrile illnesses. However, in endemic areas, parasitological confirmation of parasitemia is often unavailable or unreliable. False-positive malaria microscopy is common. ... -
Isolation and characterization of microsatellite markers in the newly discovered invasive fruit fly pest in Africa, Bactrocera invadens (Diptera: Tephritidae).
(Molecular Ecology Resources, 2008-11)We describe the isolation and characterization of 11 polymorphic microsatellite loci from the recently discovered fruit fly pest, Bactrocera invadens. The polymorphism of these loci was tested in individual flies from two ... -
Neonatal seizures in a rural Kenyan District Hospital: aetiology, incidence and outcome of hospitalization
(BioMed Central, 2010-03)Background: Acute seizures are common among children admitted to hospitals in resource poor countries. However, there is little data on the burden, causes and outcome of neonatal seizures in sub-Saharan Africa. We ... -
Iron deficiency and acute seizures: results from children living in rural Kenya and a meta-analysis.
(Public Library of Science, 2010-11)Background: There are conflicting reports on whether iron deficiency changes susceptibility to seizures. We examined the hypothesis that iron deficiency is associated with an increased risk of acute seizures in children ... -
Clinical stroke scores for distinguishing stroke subtypes: a systematic review of diagnostic test accuracy
(2013-04)Background Stroke is a major cause of morbidity and mortality especially in low and middle income countries. Computerized tomography is used to distinguish between ischemic and hemorrhagic subtypes, but it is expensive ... -
The tympanic membrane displacement analyser for monitoring intracranial pressure in children
(Child's Nervous System, 2013-06)Purpose: Raised intracranial pressure (ICP) is a potentially treatable cause of morbidity and mortality but tools for monitoring are invasive. We sought to investigate the utility of the tympanic membrane displacement (TMD) ... -
Childhood acute non-traumatic coma: aetiology and challenges in management in resource-poor countries of Africa and Asia.
(Maney Publishing, 2013-08)OBJECTIVE: This review examines the best available evidence on the aetiology of childhood acute non-traumatic coma in resource-poor countries (RPCs), discusses the challenges associated with management, and explores ... -
Unexpected relationship between tympanometry and mortality in children with nontraumatic coma.
(American Academy of Pediatrics ., 2013-09)OBJECTIVE: We sought to further examine the relationship between tympanometry and mortality after noting an unexpected association on assessment of baseline data of a study whose primary aim was to investigate the utility ... -
Value of Plasmodium falciparum Histidine-Rich Protein 2 Level and Malaria Retinopathy in Distinguishing Cerebral Malaria From Other Acute Encephalopathies in Kenyan Children.
(Journal of Infectious Diseases Advance Access published, 2013-10-09)The diagnosis of cerebral malaria is problematic in malaria-endemic areas because encephalopathy in patients with parasitemia may have another cause. Abnormal retinal findings are thought to increase the specificity of the ... -
Abnormal Intra-aural Pressure Waves Associated with Death in African Children with acute Nontraumatic Coma.
(Nature Publishing Group, 2015)BACKGROUND: We explored the relationship between tympanic membrane displacement (TMD) measurements, a tool to monitor intracranial pressure noninvasively, and clinical features and death in children with acute coma in ... -
Acne vulgaris in general population of rural western Kenya: cross-sectional community survey
(International Society of Dermatology, 2015) -
Antimicrobial resistance patterns among E. coli isolates from children presenting with diarrhoea at a cosmopolitan hospital in Kenya
(Kenyatta University, 2015-08)Diarrhoea is a serious infection that kills at least 2 million children globally. Children under the age of 5 years are particularly predisposed to diarrhoea especially if the surrounding environment is contaminated or ... -
Crypotococcal meningitis in a none-HIV infected five month old infant with rickets: Case report
(Kenyatta University, 2015-08)Crypotococcal is an invasive fungal disease, now endemic in the tropics. It is largely transmitted through inhalation, but can be transmitted locally through skin and eyes. Mostly, it causes disease in immune compromised ... -
Early management of traumatic brain injury in a Tertiary hospital in Central Kenya: A clinical audit
(Medknow Publications, 2016)Background: Traumatic brain injury (TBI) is a major cause of death and disability worldwide and is mostly attributed to road traffic accidents in resource‑poor areas. However, access to neurosurgical care is poor in ... -
Metabolic syndrome and its components among university students in Kenya
(BioMed Central, 2017)Background: Metabolic syndrome refers to a cluster of interrelated disorders which occur together causing an increase in the risk of developing cardiovascular disease and diabetes. The university population is an ... -
Key bottlenecks to the provision of safe obstetric anaesthesia in low- income countries; a cross-sectional survey of 64 hospitals in Uganda
(BioMed Central, 2017)Background: Despite recent advances in surgery and anaesthesia which significantly improve safety, many health facilities in low-and middle-income countries (LMICs) remain chronically under-resourced with inability to ... -
Streptococcus pneumoniae serotype epidemiology among PCV-10 vaccinated and unvaccinated children at Gertrude’s Children’s Hospital, Nairobi County: a cross-sectional study
(F1000Research, 2018)Background: Streptococcus pneumoniae (SPn) serotype replacement and emergence of multidrug resistant SPn has exacerbated the need for continuous regional serotype surveillance. We investigated SPn serotypes circulating among ... -
Dyslipidemia in blood pressure control among adult hypertensive patients in Kiambu County Hospital Kenya
(The East and Central Africa Medical Journal, 2020)Introduction: Hypertension is one of the most common non-communicable diseases with about 40% global prevalence in adults and 46% in Africa. Dyslipidemia, among other factors may lead to poor blood pressure control in ... -
Quality Perspective of Healthcare Provision in Selected Public Health Facilities after Devolution in Garissa County.
(International Academic Journals, 2021)Devolution is delegation of power, governance and resources from centralized government to local/subnational level jurisdictions. The Kenyan constitution allows two levels of government i.e. the national and county levels ... -
Baseline Blood Count Levels Increase Odds Of Cytopenia among CML Patients in Kenya: A Case Control Study
(Research square, 2021)Imatinib is the gold standard for the treatment of all phases of Philadelphia positive Chronic Myeloid Leukemia (CML). During treatment, patients may develop cytopenia. We aimed to study the baseline characteristics and ...
