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Adjuvants in malaria vaccine development strategies: a review
(2016-04)
Malaria leads in global rates of mortality and morbidity majorly borne by children aged below five years and primigravida women in developing countries. According to WHO, the cases of malaria infections in 2014 declined, ...
A Review of Adjuvants for Leishmania Vaccine Candidates.
(PubMed, 2010)
Over the last decade, there has been a flurry of research on adjuvants for vaccines, and several novel adjuvants are now licensed products or in late stage clinical development. The success of adjuvants in enhancing the ...
Safety and Skin Delayed-type Hypersensitivity Response in Vervet Monkeys Immunized with Leishmania Donovani Sonicate Antigen Delivered with Adjuvants
(Institute of Primate Research, 2013-01)
In this study, we report on the safety and skin delayed-type hypersensitivity (DTH), responses of the Leishmania donovani whole cell sonicate antigen delivered in conjunction with alum-BCG (AlBCG), Montanide ISA 720 (MISA) ...
Leishmania donovani whole cell antigen delivered with adjuvants protects against visceral leishmaniasis in vervet monkeys (Chlorocebus aethiops)
(2014-09-15)
In a previous immunogenicity and efficacy study in mice, montanide ISA 720 (MISA) was indicated to be a better adjuvant than bacillus calmette guerin vaccine (BCG) for a Leishmania vaccine. In the present study, we report ...