Browsing RP-School of Health Sciences by Issue Date
Now showing items 21-40 of 219
-
Trypanosoma brucei rhodesiense transmitted by a single tsetse fly bite in vervet monkeys as a model of human African trypanosomiasis.
(Public Library of Science, 2008-05-14)We have investigated the pathogenicity of tsetse (Glossina pallidipes)-transmitted cloned strains of Trypanosoma brucei rhodesiense in vervet monkeys. Tsetse flies were confirmed to have mature trypanosome infections by ... -
Polymorphic Variability in the Interleukin (IL)-1Beta Promoter Conditions Susceptibility to Severe Malarial Anemia and Functional Changes in IL-1Beta Production
(PubMed, 2008-10)Interleukin (IL)-1beta is a cytokine released as part of the innate immune response to Plasmodium falciparum. Because the role played by IL-1beta polymorphic variability in conditioning the immunopathogenesis of severe ... -
Isolation and characterization of microsatellite markers in the newly discovered invasive fruit fly pest in Africa, Bactrocera invadens (Diptera: Tephritidae).
(Molecular Ecology Resources, 2008-11)We describe the isolation and characterization of 11 polymorphic microsatellite loci from the recently discovered fruit fly pest, Bactrocera invadens. The polymorphism of these loci was tested in individual flies from two ... -
Naturally acquired hemozoin by monocytes promotes suppression of RANTES in children with malarial anemia through an IL-10-dependent mechanism.
(Microbes and Infection, 2009)Regulated upon activation, normal T-cell expressed, and secreted (RANTES, CCL-5) is an important immunoregulatory mediator that is suppressed in children with malarial anemia (MA). Although proinflammatory (e.g. TNF-α, ... -
Towards achieving millenium development goal number 5: maternal mortaility at Thika District Hospital, Kenya. A one year review
(Elsevier, 2009)Background: Maternal mortality remains high in the developing countries and especially in the Sub Saharan Africa. Constant reviews will help in elucidating varies causes which in most instance are avoidable. These will ... -
Prevalence and Antimicrobial Susceptibility of Enterobacteriaceae Collected from Patients with Wounds at Kenyatta National Hospital
(2009)Prevalence and sensitivity trends of Enterobacteriaceae isolated from septic wounds were determined through a prospective cross sectional study. One hundred and fifteen specimens isolated from in-patients in the Department ... -
Urolithiasis in Nairobi, Kenya.
(Kenya Medical Association, 2010)Background: Urolithiasis is an emerging problem in Kenya previously thought to be very rare and in which the use of modern methods of treatment has not been widely practiced Objective: To review the presentation and ... -
Hearing Disorders in HIV Positive Adult Patients
(East and Central African Journal of Surgery, 2010)Background: This study was aimed at determining the prevalence and type of hearing disorders in HIV positive patients and any correlationship with the CD4 counts/stage of HIV/AIDS in patients attending the comprehensive ... -
The levels of CD16/Fc gamma receptor IIIA on CD14+ CD16+ monocytes are higher in children with severe Plasmodium falciparum anemia than in children with cerebral or uncomplicated malaria.
(PubMed, 2010)Fc gamma receptor IIIA (CD16/Fc gamma RIIIA) on monocytes/macrophages may play an important role in the pathogenesis of severe malarial anemia (SMA) by promoting phagocytosis of IgG-coated uninfected red cells and by ... -
A novel functional variant in the stem cell growth factor promoter protects against severe malarial anemia.
(Infection and Immunity, 2010-01)Plasmodium falciparum malaria is a leading global cause of infectious disease burden. In areas in which P. falciparum transmission is holoendemic, such as western Kenya, severe malarial anemia (SMA) results in high rates ... -
Occupational Noise- Induced Hearing Loss (NIHL) among Workers at Jomo Kenyatta International Airport, Nairobi
(2010-02)BACKGROUND: Occupational noise induced hearing loss (NIHL) occurs among workers exposed to excessive amounts of noise for long durations. The average level of noise in some locations at Jomo Kenyatta International Airport ... -
Neonatal seizures in a rural Kenyan District Hospital: aetiology, incidence and outcome of hospitalization
(BioMed Central, 2010-03)Background: Acute seizures are common among children admitted to hospitals in resource poor countries. However, there is little data on the burden, causes and outcome of neonatal seizures in sub-Saharan Africa. We ... -
Acute Medical Conditions in under Five Year Old Children at a Public Hospital in Kenya.
(East African Medical Journal, 2010-08)OBJECTIVE: To determine the prevalence of childhood preventable and treatable medical conditions and the parent's/guardian's knowledge about the conditions and their management. DESIGN: A descriptive cross-sectional ... -
Hearing disorders in HIV positive adult patients not on anti-retroviral drugs at Kenyatta National Hospital
(East African Medical Journal, 2010-09)Objectives: To determine the prevalence and type of hearing disorders in HIV positive patients not on anti - retroviral drugs (ARVs) and correlate this with the world health Organization (WHO) stage of HIV disease and CD4 ... -
The pattern of hearing disorders in HIV positive patients on antiretroviral drugs at Kenyatta national hospital
(East African Medical Journal, 2010-10)Objectives: To determine if patients on Anti - retroviral drugs (ARVs) develop hearing impairment. Design: The comprehensive care clinic (CCC), Kenyatta National Hospital (KNH), Nairobi. Setting : Case controlled ... -
Iron deficiency and acute seizures: results from children living in rural Kenya and a meta-analysis.
(Public Library of Science, 2010-11)Background: There are conflicting reports on whether iron deficiency changes susceptibility to seizures. We examined the hypothesis that iron deficiency is associated with an increased risk of acute seizures in children ... -
Water Risk Factors Pre-Disposing the Under Five Children to Diarrhoeal Morbidity in Mandera District, Kenya.
(PubMed, 2010-12)OBJECTIVE: The main causes of mortality and morbidity in Mandera are conditions related to inadequate water and sanitation such as diarrhoea, which has led to malnutrition and mortality among children under five years. ... -
Functional promoter haplotypes of interleukin-18 condition susceptibility to severe malarial anemia and childhood mortality.
(PubMed, 2011)Severe malarial anemia (SMA) is a leading cause of morbidity and mortality in children residing in regions where plasmodium falciparum transmission is holoendemic. Although largely unexplored in children with SMA, ... -
Optimization of the Period of Steeping and Germination for Amaranth Grain
(Journal of Agriculture and Food Technology, 2011)
