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Immunization of Mice and Baboons with the Recombinant Sm28GST Affects Both Worm Viability and Fecundity after Experimental Infection with Schistosoma Mansoni.
(PubMed, 1991-09)A member of the glutathione S-transferase family, Sm28GST has previously demonstrated a good ability to protect rodents against experimental infection with Schistosoma mansoni. In order to evaluate its efficacy in a model ... -
Immune Complex Levels in Children with Severe Plasmodium Falciparum Malaria.
(The American Society of Tropical Medicine, 2000-05)Malaria infection leads to the formation of circulating immune complexes. However, it is unclear whether these complexes play a role in the pathogenesis of complicated Plasmodium falciparum malaria. This study aimed at ... -
Partner notification in the management of sexually transmitted infections in Nairobi, Kenya
(Kenya Medical Association, 2003)Objective: To assess utilization of partner notification as a tool in prevention and control of Sexually transmitted infections in Nairobi City Council clinics. Design: A cross-sectional study carried out between April ... -
Quality of care provided to febrile children presenting in rural private clinics on the Kenyan coast
(Makerere University Medical School, 2004)Background: Private sector health facilities are diverse in nature, and offer widely varying quality of care (QOC). Objectives: The study aimed to describe the QOC provided to febrile children at rural private clinics on ... -
Maternal Use of Insecticide-treated Nets in the Prevention of Malaria among Children under Five Years in Nyamira district, Kenya.
(East African medical journal, 2005-10)BACKGROUND: Insecticide treated nets (ITNs) have been proved as one of the most effective ways of reducing malaria morbidity and mortality in children and pregnant women. Proper use and care of insecticide treated nets ... -
Knowledge, Attitude and Practice Towards HIV/AIDS in a Rural Kenyan Community
(Cambridge University Press, 2006)The aim of this research was to explore people’s knowledge, attitude, behaviour and practice towards HIV/AIDS and sexual activity in rural Kenya, where HIV is widespread. The study community was located in south-eastern ... -
Association of FCgamma receptor IIA (CD32) polymorphism with malarial anemia and high-density parasitemia in infants and young children.
(American Journal of Tropical Medicine and Hygiene, 2006-04) -
Suppression of RANTES in children with Plasmodium falciparum malaria.
(Haematologica, 2006-10)Severe malarial anemia (MA) is the primary manifestation of severe malaria among children in areas of holoendemic Plasmodium falciparum transmission. Although overproduction of inflammatory-derived cytokines are implicated ... -
Prescription Audit Carried Out at the Pharmacy Practice Centre of the University of Nairobi between June and November 2004.
(2007)A retrospective descriptive study was carried out from June to November 2004 in a retail pharmacy situated at the School of Pharmacy, University of Nairobi within the Kenyatta National Hospital complex. The objective was ... -
Environmental Covariates of Anopheles Arabiensis in a Rice Agroecosystem in Mwea, Central Kenya
(2007)Water quality of aquatic habitats is an important determinant of female mosquito oviposition and successful larval development. This study examined the influence of environmental covariates on Anopheles arabiensis mosquito ... -
Combining Evidence of Natural Selection with Association Analysis Increases Power to Tetect Malaria-Resistance Variants.
(PubMed, 2007)Statistical power to detect disease variants can be increased by weighting candidates by their evidence of natural selection. To demonstrate that this theoretical idea works in practice, we performed an association study ... -
Injury Pattern among Non-fatal Road Traffic Crash Victims
(East African Orthopaedic Journal, 2007)Objective: To study and analyse the pattern of injuries among non-fatal road traffic crash victims. Design: Retrospective analytical study. Setting: Kenyatta National Hospital, Nairobi over a six-month period from February ... -
Antimicrobial Resistant Pattern among Foodhandlers in Nairobi (Kenya)
(2007)Antibiotic resistance represents a serious problem for clinicians, veterinarians, community and government at large. This involves cost implications as far as treatment is concerned. Multiple drug resistance as a result ... -
Over-diagnosis and co-morbidity of severe malaria in African children: a guide for clinicians.
(The American Journal of Tropical Medicine and Hygiene, 2007-12)Severe malaria is clinically similar to other severe febrile illnesses. However, in endemic areas, parasitological confirmation of parasitemia is often unavailable or unreliable. False-positive malaria microscopy is common. ... -
Growth Disruption Activity of Polar Extracts from Kotschya Uguenensis (Fabaceae) against Anopheles Gambiae S.S. (Diptera: Culicidae) Larvae
(2008)Studies on the larvicidal properties of extracts and fractions from Kotschya uguenensis Verdc. were done by long-term exposure of Anopheles gambiae s.s. larvae. The cumulative mean percentage mortalities and deformities ... -
Recycling of wastes as a strategy for environmental conservation in the Lake Victoria Basin: The case of women groups in Kisumu, Kenya
(Academic Journals, 2008)This paper examines the roles, opportunities and challenges that women groups in Kisumu City face as they recycle polythene papers and water hyacinth plant materials to make various saleable products such as bags, mats ... -
Repellency property of long chain aliphatic methyl ketones against Anopheles gambiae s.s
(African Journals Online, 2008)Long chain aliphatic methyl ketone series of C7-C15 were tested for repellency activity against the malaria transmitting mosquito Anopheles gambiae s.s. All methyl ketones produced a dose dependent (P<0.001) repellency response ... -
Distinct Pattern of Class and Subclass Antibodies in Immune Complexes of Children with Cerebral Malaria and Severe Malarial Anaemia.
(Parasite Immunology Journal, 2008)Plasmodium falciparum infection can lead to deadly complications such as severe malaria-associated anaemia (SMA) and cerebral malaria (CM). Children with severe malaria have elevated levels of circulating immune complexes ... -
Promotion of Neuronal Differentiation Through Activation of N-Methyl-D-Aspartate Receptors Transiently Expressed by Undifferentiated Neural Progenitor Cells in Fetal Rat Neocortex
(Wiley Library Online, 2008)Neural progenitor cell is a generic term for undifferentiated cell populations composed of neural stem, neuronal progenitor, and glial progenitor cells with abilities for self-renewal and multipotentiality. In this study, ...