Antimosquito and antimicrobial clerodanoids and a chlorobenzenoid from Tessmannia species
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Date
2010-02
Authors
Kihampa, C.
Nkunya, M. H.
Joseph, C.C.
Magesa, S.M.
Hassanali, Ahmed
Heydenreich, Matthias
Kleinpeter, E.
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Publisher
Pubmed
Abstract
The clerodane diterpenoids trans-kolavenolic acid, 18-oxocleroda-3,13(E)-dien-15-oic acid, ent-(18-hydroxycarbonyl)-cleroda-3,13(E)-dien-15-oate, 2-oxo-ent-cleroda-3,13(Z)-dien-15-oic acid and trans-2-oxo-ent-cleroda-13(Z)-en-15-oic acid, and the chlorobenzenoid O-(3-hydroxy-4-hydroxycarbonyl-5-pentylphenyl)-3-chloro-4-methoxy-6-pentyl-2-oxybenzoic acid were isolated from Tessmannia martiniana var pauloi and T. martiniana var matiniana. Structures were established based on interpretation of spectroscopic data. Some of the compounds exhibited significant antimosquito, antifungal and antibacterial activities.
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Citation
Nat Prod Commun. 2010 Feb;5(2):175-8.