Larvicidal and IGR activity of extract of Tanzanian plants against malaria vector mosquitoes
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Date
2009-06
Authors
Kihampa, Charles
Joseph, Cosam C.
Nkunya, Mayunga H.H.
Magesa, S.M.
Hassanali, Ahmed
Heydenreich, Matthias
Kleinpeter, Erich
Journal Title
Journal ISSN
Volume Title
Publisher
Pubmed
Abstract
Background & objectives: This paper reports the larvicidal activity of seventeen Tanzanian plant
species against the malaria vector, Anopheles gambiae s.s. Giles larvae. Some of the plants are used
traditionally as sources of insecticidal materials.
Methods: The crude extracts from the leaves, stem and root barks of the investigated plants were
obtained by solvent extraction and then bio-assayed following WHO protocols showed LC50 values
10 to 400 ppm after 24 h exposure. The structures were determined on interpretation of spectroscopic
data.
Results: The most active extracts were those from the stem and root barks of Annona squamosa,
Uvaria faulknerae, U. kirkii and Uvariodendron pycnophyllum, all of which had LC50 values between
10 and 100 ppm. Long-term exposure beyond 24 h also showed more susceptibility of the larvae to
the extracts. Larvae deformities by forming tail-like structures were observed for the methanol
extracts of Tessmannia martiniana var pauloi.
Interpretation & conclusion: The results suggest that the investigated plant extracts are promising
as larvicides against An. gambiae s.s. Giles mosquitoes and could be useful leads in the search for
new and biodegradable plant derived larvicide products
Description
Keywords
Anopheles gambiae s.s., botanical mosquitocides, IGR activity
Citation
J Vector Borne Dis 46, June 2009, pp. 145–152