Odalo, Josiah OchiengSamwel, S.Nkunya, M. H.Joseph, C. C.Koorbanally, N. A..2014-01-162014-01-162011-10Phytochemistry. 2011 Oct;72(14-15):1826-32.http://ir-library.ku.ac.ke/handle/123456789/8624doi: 10.1016/j.phytochem.2011.05.010.Toussaintine A (N-cinnamoyl-5,6-dehydro-4-hydroxyindolidin-2,7-dione), toussaintine B (N-cinnamoyl-5,6-dehydro-4,7-dihydroxyindolidin-2-one), toussaintine C (N-cinnamoyl-5,6-dehydro-4-hydroxyindolidin-7-one), toussaintine D (N-cinnamoyl-2-amino-4-hydroxy-7-oxo-2,3,8,9-tetrahydrobenzofuran) and toussaintine E (N-cinnamoyl-1-acetoxymethyl-2-amino-1-hydroxycyclox-5-en-4-one) were isolated as antibacterial and antifungal constituents of the leaves of Toussaintia orientalis Verdc. (Annonaceae) and their structures established from analysis of spectroscopic data. The compounds belong to a series of variously cyclized aminocinnamoyl tetraketide derivatives, showing the importance of rarely occurring Annonaceae species as sources of structurally diverse natural products.enToussaintines A-E: Antimicrobial Indolidinoids, a Cinnamoylhydrobenzofuranoid and a Cinnamoylcyclohexenoid from Toussaintia Orientalis Leaves.Article